ß-barrel Channel Proteins as Tools in Nanotechnology

Biology, Basic Science and Advanced Applications

Nonfiction, Health & Well Being, Medical, Medical Science, Genetics, Science & Nature, Science, Biological Sciences, Biochemistry
Cover of the book ß-barrel Channel Proteins as Tools in Nanotechnology by Marco Fioroni, Tamara Dworeck, Francisco Rodriguez-Ropero, Springer Netherlands
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Author: Marco Fioroni, Tamara Dworeck, Francisco Rodriguez-Ropero ISBN: 9789400774292
Publisher: Springer Netherlands Publication: November 4, 2013
Imprint: Springer Language: English
Author: Marco Fioroni, Tamara Dworeck, Francisco Rodriguez-Ropero
ISBN: 9789400774292
Publisher: Springer Netherlands
Publication: November 4, 2013
Imprint: Springer
Language: English

ß-barrel outer membrane channel proteins (OMP) are useful as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. It gives a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel will be outlined. An exhaustive description of the scientific strategy, including protein selection, analytical methods and “in-silico” tools to support the planning of protein modifications for a targeted application, consideration on the production of a custom made OMP, and an overview on technological applications including membrane/polymersome technology, will be provided.

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ß-barrel outer membrane channel proteins (OMP) are useful as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. It gives a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel will be outlined. An exhaustive description of the scientific strategy, including protein selection, analytical methods and “in-silico” tools to support the planning of protein modifications for a targeted application, consideration on the production of a custom made OMP, and an overview on technological applications including membrane/polymersome technology, will be provided.

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