Acute Myelogenous Leukemia in Childhood

Implications of Therapy Studies for Future Risk-Adapted Treatment Strategies

Nonfiction, Health & Well Being, Medical, Specialties, Pediatrics, Oncology
Cover of the book Acute Myelogenous Leukemia in Childhood by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783642753510
Publisher: Springer Berlin Heidelberg Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9783642753510
Publisher: Springer Berlin Heidelberg
Publication: December 6, 2012
Imprint: Springer
Language: English

The results of treatment for childhood acute myelogenous leukemia (AML) have improved considerably during the last ten years. This progress was demonstrated by the two consecutive multicenter studies, AML-BFM-78 and -83, in which almost identical extended multi drug regimes of che­ motherapy were administered for eight weeks and followed up by two years maintenance. The main difference in the second study was the addition of an eight-day intensive in­ duction course. Due to this new element, the relapse rate was reduced significantly. Another result of the BFM-83 study was the definition of two risk groups on the basis of standardized treatment, which has lead to a risk-adapted treatment strategy in the third ongoing trial, AML-BFM- 87. This improvement was only possible thanks to the coop­ eration of pediatricians, physicians, radiotherapists, statisti­ cians, and especially the staff at the hospitals and reference laboratories. Thus, we would like to thank everyone who has been involved in these studies and hope that they will be further encouraged to improve treatment strategies for AML in children. The coordination, enforcement, and analyses of the stud­ ies would not have been possible without the financial sup­ port of the Federal Ministry for Research and Technology of the FRG. We are grateful for the generous contributions supporting this book from Lederle and Farmitalia. Munster, April 1990 Ursula Creutzig Jorg Ritter Gunther Schellong Contents 1 Introduction . . . . .. . . . . . . . . . . . . . . .. . . . 1 .

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The results of treatment for childhood acute myelogenous leukemia (AML) have improved considerably during the last ten years. This progress was demonstrated by the two consecutive multicenter studies, AML-BFM-78 and -83, in which almost identical extended multi drug regimes of che­ motherapy were administered for eight weeks and followed up by two years maintenance. The main difference in the second study was the addition of an eight-day intensive in­ duction course. Due to this new element, the relapse rate was reduced significantly. Another result of the BFM-83 study was the definition of two risk groups on the basis of standardized treatment, which has lead to a risk-adapted treatment strategy in the third ongoing trial, AML-BFM- 87. This improvement was only possible thanks to the coop­ eration of pediatricians, physicians, radiotherapists, statisti­ cians, and especially the staff at the hospitals and reference laboratories. Thus, we would like to thank everyone who has been involved in these studies and hope that they will be further encouraged to improve treatment strategies for AML in children. The coordination, enforcement, and analyses of the stud­ ies would not have been possible without the financial sup­ port of the Federal Ministry for Research and Technology of the FRG. We are grateful for the generous contributions supporting this book from Lederle and Farmitalia. Munster, April 1990 Ursula Creutzig Jorg Ritter Gunther Schellong Contents 1 Introduction . . . . .. . . . . . . . . . . . . . . .. . . . 1 .

More books from Springer Berlin Heidelberg

Cover of the book Does International Trade Need a Doctrine of Transnational Law? by
Cover of the book Koordinationschemie by
Cover of the book Advanced Surgical Facial Rejuvenation by
Cover of the book Controlled Synthesis of Pt-Ni Bimetallic Catalysts and Study of Their Catalytic Properties by
Cover of the book CSR in Nordrhein-Westfalen by
Cover of the book “Two Butterflies on My Head...” by
Cover of the book MRI of the Body by
Cover of the book Scientific Computing and Cultural Heritage by
Cover of the book Pancreatic Fistulas by
Cover of the book Automated Design of Analog and High-frequency Circuits by
Cover of the book Prozess- und Anlagensicherheit by
Cover of the book Skeletterkrankungen by
Cover of the book Models and Methods of Magnetotellurics by
Cover of the book China and International Human Rights by
Cover of the book Gletscher im Wandel by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy