Advances in Down Syndrome Research

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Neuroscience, General
Cover of the book Advances in Down Syndrome Research by , Springer Vienna
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783709167212
Publisher: Springer Vienna Publication: March 13, 2013
Imprint: Springer Language: English
Author:
ISBN: 9783709167212
Publisher: Springer Vienna
Publication: March 13, 2013
Imprint: Springer
Language: English

"Advances in Down Syndrome Research” represents updated research in several areas of Down Syndrome (DS). A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell studies and in terms of biochemistry, relevance of studies on a specific protein kinase, channels, transporters, superoxide dismutase, antioxidant system, chromosome assembly factor and other important biological structures are provided. And again, the gene dosage hypothesis is addressed and although the vast majority of chromosome 21 gene products is unchanged in fetal DS brain, a few specific chromosome 21 encoded structures including transcription factors are indeed overexpressed although findings in fetal DS are different from those in adult DS brain when Alzheimer-like neuropathology supervenes.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

"Advances in Down Syndrome Research” represents updated research in several areas of Down Syndrome (DS). A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell studies and in terms of biochemistry, relevance of studies on a specific protein kinase, channels, transporters, superoxide dismutase, antioxidant system, chromosome assembly factor and other important biological structures are provided. And again, the gene dosage hypothesis is addressed and although the vast majority of chromosome 21 gene products is unchanged in fetal DS brain, a few specific chromosome 21 encoded structures including transcription factors are indeed overexpressed although findings in fetal DS are different from those in adult DS brain when Alzheimer-like neuropathology supervenes.

More books from Springer Vienna

Cover of the book Stereotactic Treatment of Epilepsy by
Cover of the book Early Brain Injury or Cerebral Vasospasm by
Cover of the book The Iceman and his Natural Environment by
Cover of the book Computational Medicine by
Cover of the book Advances in Stereotactic and Functional Neurosurgery 4 by
Cover of the book Molecular Vaccines by
Cover of the book Atlas of Neuromuscular Diseases by
Cover of the book Cerebral Visual Impairment in Children by
Cover of the book Early Markers in Parkinson’s and Alzheimer’s Diseases by
Cover of the book Kinetics of Enzyme-Modifier Interactions by
Cover of the book Ras Superfamily Small G Proteins: Biology and Mechanisms 1 by
Cover of the book Transesophageal Echocardiography by
Cover of the book Peripheral Nerve Block by
Cover of the book Angiogenesis and Vascularisation by
Cover of the book Global Positioning System by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy