Anxiolytic β-Carbolines

From Molecular Biology to the Clinic

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology, Specialties, Psychiatry
Cover of the book Anxiolytic β-Carbolines by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783642784514
Publisher: Springer Berlin Heidelberg Publication: March 7, 2013
Imprint: Springer Language: English
Author:
ISBN: 9783642784514
Publisher: Springer Berlin Heidelberg
Publication: March 7, 2013
Imprint: Springer
Language: English

Since the discovery some 15 years ago of benzodiazepine modulatory sites associated with GABA A receptors, great effort has gone into understanding their molecular pharmacology and into developing new anxiolytic drugs that interact selectively with them. Prominent in this research has beenthe discovery that ~-carbolines, a different chemical class from benzodiazepines, also act at these receptors but that their effects are sometimes quite different from those of the benzodiazepines.This book documents the latest discoveries in the molecular biology of the GABA A receptor and reveals how an integration of the results of research inmolecular biology, synthetic chemistry, biochemical and behavioral pharmacology, and clinical pharmacology has paved the way forthe development of ~-carbolines from substances inducing anxiety and convulsions to a novel therapy for anxiety states, achieving a behavioral selectivity through selective actions at subtypes of receptors.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Since the discovery some 15 years ago of benzodiazepine modulatory sites associated with GABA A receptors, great effort has gone into understanding their molecular pharmacology and into developing new anxiolytic drugs that interact selectively with them. Prominent in this research has beenthe discovery that ~-carbolines, a different chemical class from benzodiazepines, also act at these receptors but that their effects are sometimes quite different from those of the benzodiazepines.This book documents the latest discoveries in the molecular biology of the GABA A receptor and reveals how an integration of the results of research inmolecular biology, synthetic chemistry, biochemical and behavioral pharmacology, and clinical pharmacology has paved the way forthe development of ~-carbolines from substances inducing anxiety and convulsions to a novel therapy for anxiety states, achieving a behavioral selectivity through selective actions at subtypes of receptors.

More books from Springer Berlin Heidelberg

Cover of the book JIMD Reports, Volume 33 by
Cover of the book Introduction to the Physics of Massive and Mixed Neutrinos by
Cover of the book Start of a Glacial by
Cover of the book Cybernetic Approach to Project Management by
Cover of the book Many-Body Schrödinger Dynamics of Bose-Einstein Condensates by
Cover of the book Surgical Treatment of Bronchial Carcinoma by
Cover of the book Test-Driven Development by
Cover of the book Palliativversorgung und Trauerbegleitung in der Neonatologie by
Cover of the book Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism by
Cover of the book Transition Metal Catalyzed Carbonylation Reactions by
Cover of the book Diskrete Mathematik: Geordnete Mengen by
Cover of the book Drug Delivery in Cancer Treatment III by
Cover of the book Soil Enzymology in the Recycling of Organic Wastes and Environmental Restoration by
Cover of the book Rational Phytotherapy by
Cover of the book Mathematik für die berufliche Oberschule by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy