Arteriogenesis - Prognosis and Therapeutical Potential

Prognosis and Therapeutical Potential

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, General
Cover of the book Arteriogenesis - Prognosis and Therapeutical Potential by Darius Henatsch, GRIN Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Darius Henatsch ISBN: 9783640429639
Publisher: GRIN Publishing Publication: September 18, 2009
Imprint: GRIN Publishing Language: English
Author: Darius Henatsch
ISBN: 9783640429639
Publisher: GRIN Publishing
Publication: September 18, 2009
Imprint: GRIN Publishing
Language: English

Essay from the year 2008 in the subject Medicine - Internal Medicine, grade: Excellent , Maastricht University, course: Cardiology and Vascular Medicine , language: English, abstract: Due to the fast growing field of molecular cardiology, mechanisms responsible for collateral artery growth (arteriogenesis) are widely unravelled. After coronary artery occlusion, flow shear stress induces endothelial cell expression and release of adhesion molecules and chemokines. Monocytes are attracted and transmigrate into the vessel wall to release pro-arteriogenic molecules. The process of collateral vessel growth is severely impaired in patients with different risk factors for atherosclerosis, as diabetes or hyperlipedemia. This can be attributed to the impaired migration capacity of monocytes towards pro-arteriogenic stimuli, like MCP-1 and VEGF-A. In these patients 'at risk', blood derived monocytes offer a possibility to predict the individual ability to form functional collaterals by an in vitro performed migration assay. Furthermore, growth factor therapy can be used to enhance and restore collateral growth in patients with impaired arteriogenesis. Here, the migration assay could perfectly be used to for individual adjustment of therapeutical interventions.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Essay from the year 2008 in the subject Medicine - Internal Medicine, grade: Excellent , Maastricht University, course: Cardiology and Vascular Medicine , language: English, abstract: Due to the fast growing field of molecular cardiology, mechanisms responsible for collateral artery growth (arteriogenesis) are widely unravelled. After coronary artery occlusion, flow shear stress induces endothelial cell expression and release of adhesion molecules and chemokines. Monocytes are attracted and transmigrate into the vessel wall to release pro-arteriogenic molecules. The process of collateral vessel growth is severely impaired in patients with different risk factors for atherosclerosis, as diabetes or hyperlipedemia. This can be attributed to the impaired migration capacity of monocytes towards pro-arteriogenic stimuli, like MCP-1 and VEGF-A. In these patients 'at risk', blood derived monocytes offer a possibility to predict the individual ability to form functional collaterals by an in vitro performed migration assay. Furthermore, growth factor therapy can be used to enhance and restore collateral growth in patients with impaired arteriogenesis. Here, the migration assay could perfectly be used to for individual adjustment of therapeutical interventions.

More books from GRIN Publishing

Cover of the book Dewey versus Illich: Alternative Educational Utopias. by Darius Henatsch
Cover of the book Price-competition at the German mobile market by Darius Henatsch
Cover of the book Tata Acquires Corus: A case Study by Darius Henatsch
Cover of the book Empathy in Kazuo Ishiguro´s 'Never Let Me Go' by Darius Henatsch
Cover of the book The Credit on Real Estate - Local Value and Relevance for the Construction Financing in Germany and Denmark by Darius Henatsch
Cover of the book Exclamative sentences - a basic sentence type? by Darius Henatsch
Cover of the book English as a second language and naturalistic learning by Darius Henatsch
Cover of the book A Study of Sharpe's asymmetric beta model by Darius Henatsch
Cover of the book Advertising in Europe: Advertising as Communication / The World of Advertising by Darius Henatsch
Cover of the book Governance through Europeanisation of Regional Administration? - A Network Analysis of Baden-Württemberg s European Strategy by Darius Henatsch
Cover of the book Stigmatization of HIV-infected individuals by Darius Henatsch
Cover of the book The representation of immigrant life in Upton Sinclair's 'The Jungle' by Darius Henatsch
Cover of the book Selling Intervention by Darius Henatsch
Cover of the book Russian Nationalism, 1856-1917 by Darius Henatsch
Cover of the book Activity-Based-Costing (ABC) by Darius Henatsch
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy