Biology of C Reactive Protein in Health and Disease

Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Health & Well Being, Medical, Medical Science, Physiology
Cover of the book Biology of C Reactive Protein in Health and Disease by Waliza Ansar, Shyamasree Ghosh, Springer India
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Author: Waliza Ansar, Shyamasree Ghosh ISBN: 9788132226802
Publisher: Springer India Publication: March 23, 2016
Imprint: Springer Language: English
Author: Waliza Ansar, Shyamasree Ghosh
ISBN: 9788132226802
Publisher: Springer India
Publication: March 23, 2016
Imprint: Springer
Language: English

This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution.  Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP’s significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail.  The book also includes clinical data studies and presents the latest research advances to further readers’ understanding of CRP. 

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This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution.  Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP’s significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail.  The book also includes clinical data studies and presents the latest research advances to further readers’ understanding of CRP. 

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