Concepts, Structure Design and Methods from ADME to Toxicity Optimization
by
Li Di, Edward H Kerns
Language: English
Release Date: December 17, 2015
Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully...