Cancer Biomarkers in Body Fluids

Biomarkers in Circulation

Nonfiction, Health & Well Being, Medical, Medical Science, Genetics, Specialties, Oncology
Cover of the book Cancer Biomarkers in Body Fluids by Gabriel D. Dakubo, Springer International Publishing
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Author: Gabriel D. Dakubo ISBN: 9783319483603
Publisher: Springer International Publishing Publication: November 23, 2016
Imprint: Springer Language: English
Author: Gabriel D. Dakubo
ISBN: 9783319483603
Publisher: Springer International Publishing
Publication: November 23, 2016
Imprint: Springer
Language: English

This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.

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This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.

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