Cardiovascular Specific Gene Expression

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Cardiology, Science & Nature, Science, Biological Sciences, Zoology
Cover of the book Cardiovascular Specific Gene Expression by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789401593212
Publisher: Springer Netherlands Publication: April 17, 2013
Imprint: Springer Language: English
Author:
ISBN: 9789401593212
Publisher: Springer Netherlands
Publication: April 17, 2013
Imprint: Springer
Language: English

Improving our insights into the genetic predisposition to cardiovascular disease is one of the most important challenges in our field in the next millennium, not only to unravel the cause of disease but also to improve the selection of patients for particular treatments. Nowadays, for example, subjects with a cholesterol above a particular plasma level are exposed to a cholesterol lowering regime based upon the beneficial outcome of epidemiological studies which include subjects not prone to the disease, despite a plasma cholesterol above the accepted level. Identification of the patients who are genetically predisposed to the consequences of this disorder will reduce the number of subjects unnecessarily treated and, hence, the costs of health care. Because in most cardiovascular diseases the genetic component is a consequence of more than one gene defect, only limited progress has as yet been made in identifying subjects genetically at risk. For example, in hypertension only in less than 10% of the patients the genetic defect has been identified. It has been known for quite some time that in heart and blood vessels fetal genes are as high blood pressure and upregulated or induced when they are exposed to such disorders ischemia. Little is known about the function of these genes in the cardiac and vascular adaptation to these disorders; only guesses can be made.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Improving our insights into the genetic predisposition to cardiovascular disease is one of the most important challenges in our field in the next millennium, not only to unravel the cause of disease but also to improve the selection of patients for particular treatments. Nowadays, for example, subjects with a cholesterol above a particular plasma level are exposed to a cholesterol lowering regime based upon the beneficial outcome of epidemiological studies which include subjects not prone to the disease, despite a plasma cholesterol above the accepted level. Identification of the patients who are genetically predisposed to the consequences of this disorder will reduce the number of subjects unnecessarily treated and, hence, the costs of health care. Because in most cardiovascular diseases the genetic component is a consequence of more than one gene defect, only limited progress has as yet been made in identifying subjects genetically at risk. For example, in hypertension only in less than 10% of the patients the genetic defect has been identified. It has been known for quite some time that in heart and blood vessels fetal genes are as high blood pressure and upregulated or induced when they are exposed to such disorders ischemia. Little is known about the function of these genes in the cardiac and vascular adaptation to these disorders; only guesses can be made.

More books from Springer Netherlands

Cover of the book Mental Health in South Asia: Ethics, Resources, Programs and Legislation by
Cover of the book Analysing China's Population by
Cover of the book Cellular and Molecular Aspects of Plant-Nematode Interactions by
Cover of the book Management and Economic Development by
Cover of the book Anthony Collins The Man and His Works by
Cover of the book Anyone Who Has a View by
Cover of the book Cell Fusion in Health and Disease by
Cover of the book Nanotechnology in the Security Systems by
Cover of the book Numerical Linear Algebra in Signals, Systems and Control by
Cover of the book Crop Stress and its Management: Perspectives and Strategies by
Cover of the book Mapping Across Academia by
Cover of the book Free Markets and the Culture of Common Good by
Cover of the book Theological Analyses of the Clinical Encounter by
Cover of the book Climate in Human Perspective by
Cover of the book Energy for Development by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy