Cell Surface GRP78, a New Paradigm in Signal Transduction Biology

Nonfiction, Science & Nature, Science, Biological Sciences, Biology
Cover of the book Cell Surface GRP78, a New Paradigm in Signal Transduction Biology by , Elsevier Science
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Author: ISBN: 9780128123522
Publisher: Elsevier Science Publication: March 20, 2018
Imprint: Academic Press Language: English
Author:
ISBN: 9780128123522
Publisher: Elsevier Science
Publication: March 20, 2018
Imprint: Academic Press
Language: English

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78.

  • Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies
  • Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease
  • Provides four-color illustrations that facilitate the narrative
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Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78.

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