Cellular and Molecular Toxicology of Nanoparticles

Nonfiction, Science & Nature, Technology, Nanotechnology, Science, Other Sciences, Molecular Biology
Cover of the book Cellular and Molecular Toxicology of Nanoparticles by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319720418
Publisher: Springer International Publishing Publication: February 16, 2018
Imprint: Springer Language: English
Author:
ISBN: 9783319720418
Publisher: Springer International Publishing
Publication: February 16, 2018
Imprint: Springer
Language: English

This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types.

Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs exposure has been included. The readers are also introduced to the less studied topic on the adsorption of biomolecules (mainly proteins) on the NPs surface, constituting the so-called “biomolecular corona”.

The book has been designed for scientists engaged in NPs toxicity research. Nonetheless, it should be of interest to a variety of scientific disciplines including marine biology, environmental pollution, genetics, pharmacology, medicine, drug and food material sciences, consumer products. Also, the compilations will be of interest to the environmental watchdogs, federal regulators, risk assessors and the policy makers.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types.

Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs exposure has been included. The readers are also introduced to the less studied topic on the adsorption of biomolecules (mainly proteins) on the NPs surface, constituting the so-called “biomolecular corona”.

The book has been designed for scientists engaged in NPs toxicity research. Nonetheless, it should be of interest to a variety of scientific disciplines including marine biology, environmental pollution, genetics, pharmacology, medicine, drug and food material sciences, consumer products. Also, the compilations will be of interest to the environmental watchdogs, federal regulators, risk assessors and the policy makers.

More books from Springer International Publishing

Cover of the book Mathematics of Program Construction by
Cover of the book Toward the Next Generation of Bystander Prevention of Sexual and Relationship Violence by
Cover of the book Sustainability in a Digital World by
Cover of the book Friendship 7 by
Cover of the book HCI in Business, Government and Organizations. Information Systems and Analytics by
Cover of the book The Intercorrelation of Traumatic Brain Injury and PTSD in Neuropsychological Evaluations by
Cover of the book Information and Communication Technologies in Education, Research, and Industrial Applications by
Cover of the book Nonlinear Control and Filtering Using Differential Flatness Approaches by
Cover of the book Complex System Modelling and Control Through Intelligent Soft Computations by
Cover of the book Electrodeposition of Nanostructured Materials by
Cover of the book Haptics: Science, Technology, and Applications by
Cover of the book Smart Card Research and Advanced Applications by
Cover of the book Jimi Hendrix and the Cultural Politics of Popular Music by
Cover of the book Advances in Microbiology, Infectious Diseases and Public Health by
Cover of the book Product Variety in Automotive Industry by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy