Chromatin Architecture

Advances From High-resolution Single Molecule DNA Imaging

Nonfiction, Science & Nature, Science, Physics, Spectrum Analysis, Other Sciences, Molecular Biology
Cover of the book Chromatin Architecture by Kirti Prakash, Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Kirti Prakash ISBN: 9783319521831
Publisher: Springer International Publishing Publication: February 20, 2017
Imprint: Springer Language: English
Author: Kirti Prakash
ISBN: 9783319521831
Publisher: Springer International Publishing
Publication: February 20, 2017
Imprint: Springer
Language: English

This book sheds new light on the current state of knowledge concerning chromatin organization. Particular emphasis is given to the new imaging potential offered by super-resolution microscopy, which allows DNA imaging with a very high labeling density.

From the early work on chromosomes by Walther Flemming in the nineteenth century to recent advances in genomics, the history of chromatin research now spans more than a century. The various milestones, such as the discovery of the double helix structure, the sequencing of the human genome, and the recent description of the genome in 3D space, show that understanding chromatin and chromosome function requires a clear understanding of its structure.

Presenting cutting-edge data from super-resolution single molecule microscopy, the book demonstrates that chromatin manifests several levels of folding, from nucleosomes to chromosomes. Chromatin domains emerge as a new fundamental building block of chromatin architecture, with functions possibly related to gene regulation.

A detailed description of chromatin folding in the pachytene stage of meiosis serves as a model for exploring this functionality, showing the apparent interplay between structure, function, and epigenetic regulation. Lastly, the book discusses possible new avenues of innovation to describe chromatin’s organization and functions.

Gathering essential insights on chromatin architecture, the book offers students an introduction to microscopy and its application to chromatin organization, while also providing advanced readers with new ideas for future research.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This book sheds new light on the current state of knowledge concerning chromatin organization. Particular emphasis is given to the new imaging potential offered by super-resolution microscopy, which allows DNA imaging with a very high labeling density.

From the early work on chromosomes by Walther Flemming in the nineteenth century to recent advances in genomics, the history of chromatin research now spans more than a century. The various milestones, such as the discovery of the double helix structure, the sequencing of the human genome, and the recent description of the genome in 3D space, show that understanding chromatin and chromosome function requires a clear understanding of its structure.

Presenting cutting-edge data from super-resolution single molecule microscopy, the book demonstrates that chromatin manifests several levels of folding, from nucleosomes to chromosomes. Chromatin domains emerge as a new fundamental building block of chromatin architecture, with functions possibly related to gene regulation.

A detailed description of chromatin folding in the pachytene stage of meiosis serves as a model for exploring this functionality, showing the apparent interplay between structure, function, and epigenetic regulation. Lastly, the book discusses possible new avenues of innovation to describe chromatin’s organization and functions.

Gathering essential insights on chromatin architecture, the book offers students an introduction to microscopy and its application to chromatin organization, while also providing advanced readers with new ideas for future research.

More books from Springer International Publishing

Cover of the book Information and Communication Technologies in Education, Research, and Industrial Applications by Kirti Prakash
Cover of the book Drugs and Social Context by Kirti Prakash
Cover of the book Physics of Quantum Rings by Kirti Prakash
Cover of the book Agile Methods by Kirti Prakash
Cover of the book Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments by Kirti Prakash
Cover of the book Collaborative Quality Assurance in Information Systems Development by Kirti Prakash
Cover of the book Agricultural Development in the World Periphery by Kirti Prakash
Cover of the book Excel 2013 for Social Sciences Statistics by Kirti Prakash
Cover of the book Data Science in Practice by Kirti Prakash
Cover of the book Modern Algorithms of Cluster Analysis by Kirti Prakash
Cover of the book Comprehensive Anatomy of Motor Functions by Kirti Prakash
Cover of the book Preparing for Brexit by Kirti Prakash
Cover of the book High Performance Computing in Science and Engineering ´15 by Kirti Prakash
Cover of the book Security with Intelligent Computing and Big-data Services by Kirti Prakash
Cover of the book Diagnostic Clusters in Shoulder Conditions by Kirti Prakash
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy