Clinical Therapy Research in the Inflammatory Diseases

This unique textbook provides information on the dramatic advances taking place in the field of inflammatory (autoimmune) diseases and their therapies. Experts in many different medical fields — allergology, dermatology, gastroenterology, pulmonology, rheumatology etc. — will describe the advances in our understanding of the most important inflammatory diseases linking basic science discoveries to the advances in therapeutics that have taken place over the past years and foreshadow even more dramatic changes which will occur in the years to come. This is a truly multi-specialty bench-to-bedside textbook that will enable readers to gain a wide-ranging but also solidly built understanding of the therapeutic areas of inflammatory diseases.

Contents:

• Novel Therapeutic Approaches for the Inflammatory Diseases:

• Clinical Therapy Research in the Inflammatory Diseases — An Overview (Ronald F van Vollenhoven)

  From Molecular Mechanisms to Personalized Therapies in Autoimmune Inflammatory Diseases (Helena Idborg and Per-Johan Jakobsson)

  B Cell-Directed Therapies for Inflammatory Diseases (Thomas Dörner and Peter E Lipsky)

  Cell-Based Therapies for Autoimmune Diseases (Per Marits, Christian Lundgren and Ola Winqvist)

• Treatment for Specific Inflammatory Diseases:

• Advances in Therapies for Rheumatoid Arthritis (Katerina Chatzidionysiou)

  Advances in Therapies for Spondyloarthropathies (Irene E van der Horst-Bruinsma)

  Advances in Therapies for Systemic Lupus Erythematosus (Noémi Győri, Chiara Tani and Marta Mosca)

  Advances in Therapies for Systemic Sclerosis (Vanessa Smith and Filip De Keyser)

  Advances in Therapeutic Strategies for Inflammatory Bowel Disease (Åsa Krantz and Sven Almer)

  Skin, a Display Organ for the Immune System — An Update on Putative Therapy Targets*(Liv Eidsmo and Mona Ståhle)*

  Advances in Therapy for Cutaneous Lupus Erythematosus (Annegret Kuhn and Aysche Landmann)

  Advances in Therapies for Interstitial Lung Diseases (Giovanni Ferrara and Magnus Sköld)

  Advances in Therapies for Multiple Sclerosis and Related Inflammatory Diseases of the CNS (Fredrik Piehl)

  Clinical Therapy Research in Allergic Diseases (Raffaela Campana, Rudolf Valenta, Jeanette Grundström, Carl Hamsten and Marianne van Hage)

  Future Prospects for the Therapies of Inflammatory Diseases (Ronald F van Vollenhoven)

Readership: Physician specialist or physicians-in-training treating patients with inflammatory diseases, researchers studying inflammatory diseases, graduate students in the fields of immunology and inflammation, advanced-level medical students, and those in the life sciences with a keen interest in the inflammatory (autoimmune) diseases.
Key Features:

• This book provides a unique view of advances in a range of inflammatory (autoimmune) disease across different medical specialties
• This book combines advances in understanding the mechanisms of autoimmune disease with the clinical applications of specific immunomodulatory therapies
• The book identifies the most promising areas of investigation occurring in the present, which will change therapies in the years and decades to come