Comparative Biology of Aging

Nonfiction, Health & Well Being, Medical, Specialties, Geriatrics, Science & Nature, Science, Biological Sciences, Cytology
Cover of the book Comparative Biology of Aging by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789048134656
Publisher: Springer Netherlands Publication: January 8, 2010
Imprint: Springer Language: English
Author:
ISBN: 9789048134656
Publisher: Springer Netherlands
Publication: January 8, 2010
Imprint: Springer
Language: English

determined by an inability to move in response to touch. C. elegans develop through four larval stages following hatching and prior to adulthood. Adult C. elegans are reproductive for about the rst week of adulthood followed by approximately two weeks of post-reproductive adulthood prior to death. Life span is most commonly measured in the laboratory by maintaining the worms on the surface of a nutrie- agar medium (Nematode Growth Medium, NGM) with E. coli OP50 as the bacterial food source (REF). Alternative culture conditions have been described in liquid media; however, these are not widely used for longevity studies. Longevity of the commonly used wild type C. elegans hermaphrodite (N2) varies ? from 16 to 23 days under standard laboratory conditions (20 C, NGM agar, E. coli OP50 food source). Life span can be increased by maintaining animals at lower ambient temperatures and shortened by raising the ambient temperature. Use of a killed bacterial food source, rather than live E. coli, increases lifespan by 2–4 days, and growth of adult animals in the absence of bacteria (axenic growth or bac- rial deprivation) increases median life span to 32–38 days [3, 23, 24]. Under both standard laboratory conditions and bacterial deprivation conditions, wild-derived C. elegans hermaphrodites exhibit longevity comparable to N2 animals [25].

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

determined by an inability to move in response to touch. C. elegans develop through four larval stages following hatching and prior to adulthood. Adult C. elegans are reproductive for about the rst week of adulthood followed by approximately two weeks of post-reproductive adulthood prior to death. Life span is most commonly measured in the laboratory by maintaining the worms on the surface of a nutrie- agar medium (Nematode Growth Medium, NGM) with E. coli OP50 as the bacterial food source (REF). Alternative culture conditions have been described in liquid media; however, these are not widely used for longevity studies. Longevity of the commonly used wild type C. elegans hermaphrodite (N2) varies ? from 16 to 23 days under standard laboratory conditions (20 C, NGM agar, E. coli OP50 food source). Life span can be increased by maintaining animals at lower ambient temperatures and shortened by raising the ambient temperature. Use of a killed bacterial food source, rather than live E. coli, increases lifespan by 2–4 days, and growth of adult animals in the absence of bacteria (axenic growth or bac- rial deprivation) increases median life span to 32–38 days [3, 23, 24]. Under both standard laboratory conditions and bacterial deprivation conditions, wild-derived C. elegans hermaphrodites exhibit longevity comparable to N2 animals [25].

More books from Springer Netherlands

Cover of the book Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease by
Cover of the book The Renaissance of Confucianism in Contemporary China by
Cover of the book Ethics and Law in Modern Medicine by
Cover of the book Law as Institution by
Cover of the book Foundations and Applications of Decision Theory by
Cover of the book Computational Vision and Medical Image Processing by
Cover of the book Educational Innovation in Economics and Business Administration: by
Cover of the book The Cambridge Diet by
Cover of the book The Chemistry of Matter Waves by
Cover of the book Bioethics with Liberty and Justice by
Cover of the book The Ecology and Semiotics of Language Learning by
Cover of the book Smaller Satellites: Bigger Business? by
Cover of the book Handbook of Causal Analysis for Social Research by
Cover of the book Recent Progress in Coupled Cluster Methods by
Cover of the book Engineering Behaviour of Rocks by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy