Complement Therapeutics

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Science & Nature, Science, Biological Sciences, Microbiology
Cover of the book Complement Therapeutics by , Springer US
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461441182
Publisher: Springer US Publication: September 19, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781461441182
Publisher: Springer US
Publication: September 19, 2012
Imprint: Springer
Language: English

This book highlights progress and trends in the rapidly evolving field of complement-related drug discovery and spotlights examples of clinical applications. As an integral part of innate immunity and critical mediator in homeostatic and inflammatory processes, the human complement system has been identified as contributor to a large number of disorders including ocular, cardiovascular, metabolic, autoimmune, and inflammatory diseases as well as in ischemia/reperfusion injury, cancer and sepsis. In addition, complement is often involved in adverse immune reactions to biomaterials, cell and organ transplants or drug delivery systems. Although the complement cascade with its close to 50 extracellular protein targets has long been recognized as an attractive system for therapeutic modulation, the past few years have seen a particularly strong boost in interest. Fueled by novel research insight and the marketing of the first complement-targeted drugs, a plethora of highly creative treatment approaches and potent drug candidates have recently emerged and are currently evaluated in disease models and clinical trials.

 

The chapters in this book cover a wide range of topics related to the development of complement therapeutics, ranging from the molecular and functional description of complement targets to the presentation of novel inhibitors, improved treatment strategies as well as examples of disease models and clinical applications. The broad and up-to-date overview on a highly versatile and dynamic field renders this book an indispensable source of information for researchers and clinicians dealing with therapeutic and disease-related aspects of the human complement system.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This book highlights progress and trends in the rapidly evolving field of complement-related drug discovery and spotlights examples of clinical applications. As an integral part of innate immunity and critical mediator in homeostatic and inflammatory processes, the human complement system has been identified as contributor to a large number of disorders including ocular, cardiovascular, metabolic, autoimmune, and inflammatory diseases as well as in ischemia/reperfusion injury, cancer and sepsis. In addition, complement is often involved in adverse immune reactions to biomaterials, cell and organ transplants or drug delivery systems. Although the complement cascade with its close to 50 extracellular protein targets has long been recognized as an attractive system for therapeutic modulation, the past few years have seen a particularly strong boost in interest. Fueled by novel research insight and the marketing of the first complement-targeted drugs, a plethora of highly creative treatment approaches and potent drug candidates have recently emerged and are currently evaluated in disease models and clinical trials.

 

The chapters in this book cover a wide range of topics related to the development of complement therapeutics, ranging from the molecular and functional description of complement targets to the presentation of novel inhibitors, improved treatment strategies as well as examples of disease models and clinical applications. The broad and up-to-date overview on a highly versatile and dynamic field renders this book an indispensable source of information for researchers and clinicians dealing with therapeutic and disease-related aspects of the human complement system.

More books from Springer US

Cover of the book Psychiatry and Psychology in the USSR by
Cover of the book Ultrastructure of the Digestive Tract by
Cover of the book Embedded Memories for Nano-Scale VLSIs by
Cover of the book Evolutionary Psychology by
Cover of the book Treatment Strategies in Child and Adolescent Psychiatry by
Cover of the book Gems and Jewelry Appraising by
Cover of the book Problems and Solutions in Human Assessment by
Cover of the book Social Referencing and the Social Construction of Reality in Infancy by
Cover of the book Randomised Controlled Clinical Trials by
Cover of the book Lay Epistemics and Human Knowledge by
Cover of the book Health Psychology by
Cover of the book Humanistic Psychology by
Cover of the book Moisture Sensitivity of Plastic Packages of IC Devices by
Cover of the book How to Write a Successful Research Grant Application by
Cover of the book Estimating Abundance of African Wildlife by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy