Complex Systems and Computational Biology Approaches to Acute Inflammation

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Science & Nature, Science, Biological Sciences
Cover of the book Complex Systems and Computational Biology Approaches to Acute Inflammation by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461480082
Publisher: Springer New York Publication: August 15, 2013
Imprint: Springer Language: English
Author:
ISBN: 9781461480082
Publisher: Springer New York
Publication: August 15, 2013
Imprint: Springer
Language: English

The difficulty in achieving effective translation of basic mechanistic biomedical knowledge into effective therapeutics, is the greatest challenge in biomedical research. Nowhere is this more apparent than in the reductionist approaches to understanding and manipulating the acute inflammatory response in the settings of sepsis, trauma/hemorrhage, wound healing, and related processes. This book discusses complex systems and computational biology methods and approaches that have advanced sufficiently to allow for knowledge generation, knowledge integration, and clinical translation in the settings of complex diseases related to the inflammatory response. Well-regulated, self-resolving inflammation is necessary for the appropriate communication and resolution of infection and trauma, and for maintenance of proper physiology and homeostasis. In contrast, self-sustaining inflammation drives the pathobiology of the aforementioned diseases. It is now increasingly recognized that controlling and reprogramming inflammation in order to reap the benefits of this evolutionarily-conserved process is preferred to simply abolishing indiscriminately.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The difficulty in achieving effective translation of basic mechanistic biomedical knowledge into effective therapeutics, is the greatest challenge in biomedical research. Nowhere is this more apparent than in the reductionist approaches to understanding and manipulating the acute inflammatory response in the settings of sepsis, trauma/hemorrhage, wound healing, and related processes. This book discusses complex systems and computational biology methods and approaches that have advanced sufficiently to allow for knowledge generation, knowledge integration, and clinical translation in the settings of complex diseases related to the inflammatory response. Well-regulated, self-resolving inflammation is necessary for the appropriate communication and resolution of infection and trauma, and for maintenance of proper physiology and homeostasis. In contrast, self-sustaining inflammation drives the pathobiology of the aforementioned diseases. It is now increasingly recognized that controlling and reprogramming inflammation in order to reap the benefits of this evolutionarily-conserved process is preferred to simply abolishing indiscriminately.

More books from Springer New York

Cover of the book Holistic Engineering Education by
Cover of the book The Challenges of Mental Health Caregiving by
Cover of the book Practical Management of Pediatric Ocular Disorders and Strabismus by
Cover of the book The Internet for Physicians by
Cover of the book Surgical Oncology by
Cover of the book Molecular Marker Applications for Improving Sugar Content in Sugarcane by
Cover of the book Alcohol and Cancer by
Cover of the book Bioactive Polyphenols from Wine Grapes by
Cover of the book The Quality of Measurements by
Cover of the book Reviews of Environmental Contamination and Toxicology Volume 224 by
Cover of the book Manual of Cardiac Surgery by
Cover of the book Built-in-Self-Test and Digital Self-Calibration for RF SoCs by
Cover of the book The Physics of Skiing by
Cover of the book Glycoprotein Hormones by
Cover of the book Neurobiology of Interval Timing by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy