Compound Solutions

Pharmaceutical Alternatives for Global Health

Nonfiction, Health & Well Being, Medical, Reference, Research, Health Policy, Social & Cultural Studies, Social Science
Cover of the book Compound Solutions by Susan Craddock, University of Minnesota Press
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Author: Susan Craddock ISBN: 9781452953786
Publisher: University of Minnesota Press Publication: February 21, 2017
Imprint: Univ Of Minnesota Press Language: English
Author: Susan Craddock
ISBN: 9781452953786
Publisher: University of Minnesota Press
Publication: February 21, 2017
Imprint: Univ Of Minnesota Press
Language: English

Claiming 1.5 million lives in 2015, tuberculosis is the world’s most deadly infectious disease. Because of the population it overwhelmingly affects, however, pharmaceutical companies are uninterested in developing better drugs for the disease. Compound Solutions examines Product Development Partnerships (PDPs), which arose early in the twenty-first century to develop new drugs and vaccines for infectious diseases in low-income countries. Here, for the first time, is a sustained examination of PDPs: the work they do, the partnerships they form, their mission, and their underlying philosophy of addressing global health needs—with implications that extend well beyond tuberculosis.

Focusing on two PDPs for tuberculosis—the Global Alliance for TB Drug Development (TB Alliance) and Aeras (a nonprofit focused on vaccine development)—Susan Craddock argues that PDPs do much more than product development. As innovative sites of humanitarian pharmaceutical production, they are contravening mainstream pharmaceutical production by tying drug and vaccine research to global health needs rather than shareholder demand. In largely untethering the profit incentive from pharmaceutical production, Craddock shows, PDPs exhibit more creative and efficient scientific practices, reshaping regulatory norms and implementing more ethical forms of clinical trials that enhance community engagement and capacity building. 

An unparalleled, interdisciplinary analysis of PDPs as politically, socially, scientifically, and economically innovative sites of pharmaceutical production, Compound Solutions is a must for readers in the fields of public health, science and technology studies, and medical social science.

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Claiming 1.5 million lives in 2015, tuberculosis is the world’s most deadly infectious disease. Because of the population it overwhelmingly affects, however, pharmaceutical companies are uninterested in developing better drugs for the disease. Compound Solutions examines Product Development Partnerships (PDPs), which arose early in the twenty-first century to develop new drugs and vaccines for infectious diseases in low-income countries. Here, for the first time, is a sustained examination of PDPs: the work they do, the partnerships they form, their mission, and their underlying philosophy of addressing global health needs—with implications that extend well beyond tuberculosis.

Focusing on two PDPs for tuberculosis—the Global Alliance for TB Drug Development (TB Alliance) and Aeras (a nonprofit focused on vaccine development)—Susan Craddock argues that PDPs do much more than product development. As innovative sites of humanitarian pharmaceutical production, they are contravening mainstream pharmaceutical production by tying drug and vaccine research to global health needs rather than shareholder demand. In largely untethering the profit incentive from pharmaceutical production, Craddock shows, PDPs exhibit more creative and efficient scientific practices, reshaping regulatory norms and implementing more ethical forms of clinical trials that enhance community engagement and capacity building. 

An unparalleled, interdisciplinary analysis of PDPs as politically, socially, scientifically, and economically innovative sites of pharmaceutical production, Compound Solutions is a must for readers in the fields of public health, science and technology studies, and medical social science.

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