Concepts and Models for Drug Permeability Studies

Cell and Tissue based In Vitro Culture Models

Nonfiction, Science & Nature, Science, Biological Sciences, Cytology
Cover of the book Concepts and Models for Drug Permeability Studies by Bruno Sarmento, Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Bruno Sarmento ISBN: 9780081001141
Publisher: Elsevier Science Publication: September 30, 2015
Imprint: Woodhead Publishing Language: English
Author: Bruno Sarmento
ISBN: 9780081001141
Publisher: Elsevier Science
Publication: September 30, 2015
Imprint: Woodhead Publishing
Language: English

This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route.

  • Updated information regarding the most recent in vitro models to study the permeability of drugs
  • Short and concise chapters covering all the biological barriers with interest in drug permeability
  • A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models
  • Simple and clear scientific content, adaptable for young scientists and experimented researchers
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route.

More books from Elsevier Science

Cover of the book The Indian Ocean Nodule Field by Bruno Sarmento
Cover of the book Parallel Computational Fluid Dynamics '98 by Bruno Sarmento
Cover of the book Becoming a Lean Library by Bruno Sarmento
Cover of the book Computational Error and Complexity in Science and Engineering by Bruno Sarmento
Cover of the book Tamime and Robinson's Yoghurt by Bruno Sarmento
Cover of the book Computer Organization and Design, Revised Fourth Edition by Bruno Sarmento
Cover of the book Understanding Forensic Digital Imaging by Bruno Sarmento
Cover of the book Mitochondrial Function, Part A by Bruno Sarmento
Cover of the book Antimicrobial Stewardship by Bruno Sarmento
Cover of the book RNA Methodologies by Bruno Sarmento
Cover of the book Handbook of Terror Management Theory by Bruno Sarmento
Cover of the book Thor's OS Xodus by Bruno Sarmento
Cover of the book Genetics of Stem Cells by Bruno Sarmento
Cover of the book Oral Physiology by Bruno Sarmento
Cover of the book Fundamentals of Brain Network Analysis by Bruno Sarmento
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy