Cutaneous Drug Eruptions

Diagnosis, Histopathology and Therapy

Nonfiction, Health & Well Being, Medical, Specialties, Dermatology, Medical Science, Pharmacology
Cover of the book Cutaneous Drug Eruptions by , Springer London
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Author: ISBN: 9781447167297
Publisher: Springer London Publication: August 21, 2015
Imprint: Springer Language: English
Author:
ISBN: 9781447167297
Publisher: Springer London
Publication: August 21, 2015
Imprint: Springer
Language: English

​The burden of cutaneous drug reactions is significant, in both outpatient and inpatient settings,  and can result in morbidity and even mortality.  This book is unique in its approach to this problem.  This text is divided into basic principles, common drug reactions, skin conditions mimicked by drug reactions, drug reactions to the skin appendages, life-threatening drug reactions, less common drug reactions, and special groupings of drug reactions. For the clinician, the skin can only morphologically react in to many limited ways. This is also true for the pathologist.  Combining these two forever linked specialties is a synergistic paradigm that greatly enhances diagnosis, and ultimately therapy, for these pernicious conditions. Drug reactions in the skin remain a common complication of therapy.  True incidences of drug reactions are not available.  For general discussion, the rule of 3% can be applied with reasonable assuredness.  Approximately 3% of all hospitalized patients develop an adverse cutaneous drug reaction.  Approximately 3% of these reactions are considered severe.  Outpatient data is even more obscure, but at least 3% of dermatology clinic outpatient visits are due to a drug reaction.  Cutaneous drug reactions compromise approximately 3% of all drug reactions. Even more challenging is the fact that the most vulnerable populations to drug reactions are increasing and include the elderly patients on prolonged drug therapy, and patients that use multiple drugs at the same time.

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​The burden of cutaneous drug reactions is significant, in both outpatient and inpatient settings,  and can result in morbidity and even mortality.  This book is unique in its approach to this problem.  This text is divided into basic principles, common drug reactions, skin conditions mimicked by drug reactions, drug reactions to the skin appendages, life-threatening drug reactions, less common drug reactions, and special groupings of drug reactions. For the clinician, the skin can only morphologically react in to many limited ways. This is also true for the pathologist.  Combining these two forever linked specialties is a synergistic paradigm that greatly enhances diagnosis, and ultimately therapy, for these pernicious conditions. Drug reactions in the skin remain a common complication of therapy.  True incidences of drug reactions are not available.  For general discussion, the rule of 3% can be applied with reasonable assuredness.  Approximately 3% of all hospitalized patients develop an adverse cutaneous drug reaction.  Approximately 3% of these reactions are considered severe.  Outpatient data is even more obscure, but at least 3% of dermatology clinic outpatient visits are due to a drug reaction.  Cutaneous drug reactions compromise approximately 3% of all drug reactions. Even more challenging is the fact that the most vulnerable populations to drug reactions are increasing and include the elderly patients on prolonged drug therapy, and patients that use multiple drugs at the same time.

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