Deep Brain Stimulation

Indications and Applications

Nonfiction, Health & Well Being, Medical, Surgery, Neurosurgery, Specialties, Internal Medicine, Neurology, Science & Nature, Science, Biological Sciences
Cover of the book Deep Brain Stimulation by , Jenny Stanford Publishing
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Author: ISBN: 9781315341095
Publisher: Jenny Stanford Publishing Publication: December 8, 2016
Imprint: Jenny Stanford Publishing Language: English
Author:
ISBN: 9781315341095
Publisher: Jenny Stanford Publishing
Publication: December 8, 2016
Imprint: Jenny Stanford Publishing
Language: English

Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood.

Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulation–evoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.

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Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood.

Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulation–evoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.

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