Developments in T Cell Based Cancer Immunotherapies

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Specialties, Oncology
Cover of the book Developments in T Cell Based Cancer Immunotherapies by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319211671
Publisher: Springer International Publishing Publication: November 26, 2015
Imprint: Humana Language: English
Author:
ISBN: 9783319211671
Publisher: Springer International Publishing
Publication: November 26, 2015
Imprint: Humana
Language: English

This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification or reprogramming to increase their ability to survive and expand when adoptively transferred back to the patients. Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents. Furthermore, the revolutionary role of checkpoint inhibitors and their potential in combination with other immunotherapeutic approaches or with standard chemo and radiation therapy are extensively discussed.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification or reprogramming to increase their ability to survive and expand when adoptively transferred back to the patients. Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents. Furthermore, the revolutionary role of checkpoint inhibitors and their potential in combination with other immunotherapeutic approaches or with standard chemo and radiation therapy are extensively discussed.

More books from Springer International Publishing

Cover of the book How to Do Science with Models by
Cover of the book Innovation, Engineering and Entrepreneurship by
Cover of the book Irish Urban Fictions by
Cover of the book Analytic Aspects of Convexity by
Cover of the book Regenerative and Positive Impact Architecture by
Cover of the book Feferman on Foundations by
Cover of the book The Race to the Moon Chronicled in Stamps, Postcards, and Postmarks by
Cover of the book Advanced Concepts, Methodologies and Technologies for Transportation and Logistics by
Cover of the book Computer Vision and Graphics by
Cover of the book Spatial Econometric Interaction Modelling by
Cover of the book Queering Agatha Christie by
Cover of the book Organic Chemistry in Confining Media by
Cover of the book Ubiquitous Computing and Ambient Intelligence by
Cover of the book Modeling of Nanotoxicity by
Cover of the book Nanoplasmonics, Nano-Optics, Nanocomposites, and Surface Studies by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy