Dual-Mode Electro-photonic Silicon Biosensors

Nonfiction, Science & Nature, Science, Biological Sciences, Biophysics, Technology, Material Science
Cover of the book Dual-Mode Electro-photonic Silicon Biosensors by José Juan Colás, Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: José Juan Colás ISBN: 9783319605012
Publisher: Springer International Publishing Publication: July 18, 2017
Imprint: Springer Language: English
Author: José Juan Colás
ISBN: 9783319605012
Publisher: Springer International Publishing
Publication: July 18, 2017
Imprint: Springer
Language: English

This highly interdisciplinary thesis reports on two innovative photonic biosensors that combine multiple simultaneous measurements to provide unique insights into the activity and structure of surface immobilized biological molecules. In addition, it presents a new silicon photonic biosensor that exploits two cascaded resonant sensors to provide two independent measurements of a biological layer immobilized on the surface. By combining these two measurements, it is possible to unambiguously quantify the density and thickness of the molecular layer; here, the approach’s ability to study molecular conformation and conformational changes in real time is demonstrated.

The electrophotonic biosensor integrates silicon photonics with electrochemistry into a single technology. This multi-modal biosensor provides a number of unique capabilities that extend the functionality of conventional silicon photonics. For example, by combining the complementary information revealed by simultaneous electrochemical and photonic measurements, it is possible to provide unique insights into on-surface electrochemical processes. Furthermore, the ability to create electrochemical reactions directly on the silicon surface provides a novel approach for engineering the chemical functionality of the photonic sensors. The electrophotonic biosensor thus represents a critical advance towards the development of very high-density photonic sensor arrays for multiplexed diagnostics.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This highly interdisciplinary thesis reports on two innovative photonic biosensors that combine multiple simultaneous measurements to provide unique insights into the activity and structure of surface immobilized biological molecules. In addition, it presents a new silicon photonic biosensor that exploits two cascaded resonant sensors to provide two independent measurements of a biological layer immobilized on the surface. By combining these two measurements, it is possible to unambiguously quantify the density and thickness of the molecular layer; here, the approach’s ability to study molecular conformation and conformational changes in real time is demonstrated.

The electrophotonic biosensor integrates silicon photonics with electrochemistry into a single technology. This multi-modal biosensor provides a number of unique capabilities that extend the functionality of conventional silicon photonics. For example, by combining the complementary information revealed by simultaneous electrochemical and photonic measurements, it is possible to provide unique insights into on-surface electrochemical processes. Furthermore, the ability to create electrochemical reactions directly on the silicon surface provides a novel approach for engineering the chemical functionality of the photonic sensors. The electrophotonic biosensor thus represents a critical advance towards the development of very high-density photonic sensor arrays for multiplexed diagnostics.

More books from Springer International Publishing

Cover of the book Cultivating Charismatic Power by José Juan Colás
Cover of the book Emotional Feedback for Mobile Devices by José Juan Colás
Cover of the book Hybrid Energy Systems by José Juan Colás
Cover of the book Resource Allocation in Unlicensed Long Term Evolution HetNets by José Juan Colás
Cover of the book X-Ray Lasers 2016 by José Juan Colás
Cover of the book Smart Solutions in Today’s Transport by José Juan Colás
Cover of the book Atlas and Anatomy of PET/MRI, PET/CT and SPECT/CT by José Juan Colás
Cover of the book Evidence-Based Implant Dentistry by José Juan Colás
Cover of the book Information and Communication Technologies in Tourism 2016 by José Juan Colás
Cover of the book Gastrointestinal Pharmacology by José Juan Colás
Cover of the book Homological and Combinatorial Methods in Algebra by José Juan Colás
Cover of the book Game Dynamics by José Juan Colás
Cover of the book Adapting to an Uncertain Climate by José Juan Colás
Cover of the book Smart Specialisation and the Agri-food System by José Juan Colás
Cover of the book Outlier Ensembles by José Juan Colás
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy