Dynamics of Engineered Artificial Membranes and Biosensors

Nonfiction, Science & Nature, Technology, Engineering, Health & Well Being, Medical
Cover of the book Dynamics of Engineered Artificial Membranes and Biosensors by William Hoiles, Vikram Krishnamurthy, Bruce Cornell, Cambridge University Press
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Author: William Hoiles, Vikram Krishnamurthy, Bruce Cornell ISBN: 9781108530378
Publisher: Cambridge University Press Publication: April 30, 2018
Imprint: Cambridge University Press Language: English
Author: William Hoiles, Vikram Krishnamurthy, Bruce Cornell
ISBN: 9781108530378
Publisher: Cambridge University Press
Publication: April 30, 2018
Imprint: Cambridge University Press
Language: English

Learn about the state of the art in building artificial membranes and synthetic biological devices, and in constructing mathematical models for their dynamics at multiple time and spatial scales with this comprehensive book. Drawing on recent advances in bioengineering and biochemistry, it describes how to engineer tethered bilayer lipid membranes, bioelectronic interfaces, high-resolution biosensors, and diagnostic devices for non-invasive cellular measurements and electroporation. Multi-physics models combining atomistic (molecular dynamics and coarse-grained molecular dynamics), mesoscopic (Poisson–Nernst–Planck), and macroscopic (reaction-rate theory) dynamics provide a complete structure-to-function description of these devices. Experiments and dynamic models explain how anti-microbial peptides penetrate membranes, how molecular machine biosensors built out of artificial membranes can detect femtomolar concentrations, and how electroporation can be controlled. Supported by atomistic simulation code online, this is essential reading for researchers, students and professionals in bioengineering, chemical engineering, biophysics, applied mathematics, and electrical engineering.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Learn about the state of the art in building artificial membranes and synthetic biological devices, and in constructing mathematical models for their dynamics at multiple time and spatial scales with this comprehensive book. Drawing on recent advances in bioengineering and biochemistry, it describes how to engineer tethered bilayer lipid membranes, bioelectronic interfaces, high-resolution biosensors, and diagnostic devices for non-invasive cellular measurements and electroporation. Multi-physics models combining atomistic (molecular dynamics and coarse-grained molecular dynamics), mesoscopic (Poisson–Nernst–Planck), and macroscopic (reaction-rate theory) dynamics provide a complete structure-to-function description of these devices. Experiments and dynamic models explain how anti-microbial peptides penetrate membranes, how molecular machine biosensors built out of artificial membranes can detect femtomolar concentrations, and how electroporation can be controlled. Supported by atomistic simulation code online, this is essential reading for researchers, students and professionals in bioengineering, chemical engineering, biophysics, applied mathematics, and electrical engineering.

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