Evolution by Tumor Neofunctionalization

The Role of Tumors in the Origin of New Cell Types, Tissues and Organs

Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Biological Sciences, Genetics
Cover of the book Evolution by Tumor Neofunctionalization by Andrei P. Kozlov, Elsevier Science
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Author: Andrei P. Kozlov ISBN: 9780128004982
Publisher: Elsevier Science Publication: February 15, 2014
Imprint: Academic Press Language: English
Author: Andrei P. Kozlov
ISBN: 9780128004982
Publisher: Elsevier Science
Publication: February 15, 2014
Imprint: Academic Press
Language: English

Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution.

Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution.

This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology.

  • Covers the role that tumors might play in evolution.
  • Provides multidisciplinary approach that will appeal to a wide circle of professionals in the fields of evolutionary biology, oncology, molecular biology, and more
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Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution.

Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution.

This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology.

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