Extracellular Matrix in Tumor Biology

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Specialties, Oncology
Cover of the book Extracellular Matrix in Tumor Biology by , Springer International Publishing
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Author: ISBN: 9783319609072
Publisher: Springer International Publishing Publication: August 4, 2017
Imprint: Springer Language: English
Author:
ISBN: 9783319609072
Publisher: Springer International Publishing
Publication: August 4, 2017
Imprint: Springer
Language: English

This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression.  The book addresses researchers working on cancer biology or ECM, and oncologists alike.

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This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression.  The book addresses researchers working on cancer biology or ECM, and oncologists alike.

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