Fidelity and Quality Control in Gene Expression

Nonfiction, Science & Nature, Science, Biological Sciences, Biochemistry, Genetics
Cover of the book Fidelity and Quality Control in Gene Expression by Assen Marintchev, Elsevier Science
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Author: Assen Marintchev ISBN: 9780123864987
Publisher: Elsevier Science Publication: January 25, 2012
Imprint: Academic Press Language: English
Author: Assen Marintchev
ISBN: 9780123864987
Publisher: Elsevier Science
Publication: January 25, 2012
Imprint: Academic Press
Language: English

The goal of this volume is to provide a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation. In addition to discussing processes with direct contribution to translation fidelity, such as aminoacylation of tRNAs and translation elongation itself, special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting.

  • Provides a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation
  • Special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting
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The goal of this volume is to provide a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation. In addition to discussing processes with direct contribution to translation fidelity, such as aminoacylation of tRNAs and translation elongation itself, special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting.

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