Fluorine and Health

Molecular Imaging, Biomedical Materials and Pharmaceuticals

Nonfiction, Health & Well Being, Medical, Reference, Public Health
Cover of the book Fluorine and Health by , Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9780080558110
Publisher: Elsevier Science Publication: June 6, 2008
Imprint: Elsevier Science Language: English
Author:
ISBN: 9780080558110
Publisher: Elsevier Science
Publication: June 6, 2008
Imprint: Elsevier Science
Language: English

Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals.
Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries.
The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.
Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized.

- New approach of topics involving chemistry, biology and medicinal techniques
- Transdisciplinar papers on fluoride products
- Importance of fluoride products in health
- Updated data on specific topics

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals.
Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries.
The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.
Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized.

- New approach of topics involving chemistry, biology and medicinal techniques
- Transdisciplinar papers on fluoride products
- Importance of fluoride products in health
- Updated data on specific topics

More books from Elsevier Science

Cover of the book The Behavioral and Social Sciences and the Practice of Medicine by
Cover of the book Fluid Phase Behavior for Conventional and Unconventional Oil and Gas Reservoirs by
Cover of the book An Introduction to Biological Membranes by
Cover of the book Nanotechnology-Enhanced Orthopedic Materials by
Cover of the book Silicon Photonics by
Cover of the book Advances in Asphalt Materials by
Cover of the book Modern Map Methods in Particle Beam Physics by
Cover of the book Nanoparticle Technologies by
Cover of the book Handbook of Social Economics by
Cover of the book Advanced Topics in Forensic DNA Typing: Methodology by
Cover of the book The Boundary Element Method for Plate Analysis by
Cover of the book Advances in Immunology by
Cover of the book Novel Designs of Early Phase Trials for Cancer Therapeutics by
Cover of the book Elementary Molecular Quantum Mechanics by
Cover of the book Advanced Materials Science and Engineering of Carbon by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy