Hormonal Carcinogenesis III

Proceedings of the Third International Symposium

Nonfiction, Health & Well Being, Medical, Specialties, Oncology
Cover of the book Hormonal Carcinogenesis III by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461220923
Publisher: Springer New York Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781461220923
Publisher: Springer New York
Publication: December 6, 2012
Imprint: Springer
Language: English

Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer fields of molecular genetics and cytogenetics already have and are expected to continue to playa major role in furthering our understanding of the cellular and molecular events in hormonal carcinogenesis. It has become increasingly clear that the risk of naturally occurring sex hormones in carcinogenic processes, both in human and in animal models, requires only minute quantities of hormones, at both the serum and tissue levels. Moreover, hormone target tissues for neoplastic transformation, perhaps with the exception of the liver, generally have relatively modest ability to metabolize sex hormones, such as the breast and prostate. Table 1 summarizes the serum, and in most cases, the tissue levels of sex hormones, both endogenously and exogenously ingested, which are associated with increased risk for endocrine-associated cancers such as breast, endometrium, and prostate, as well as the hormone levels of four experimental models that have been shown to elicit high tumor incidences. In contrast to the human, in which the hormone levels are cyclic, however, the latter require continuous hormone exposure at these relatively low levels.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer fields of molecular genetics and cytogenetics already have and are expected to continue to playa major role in furthering our understanding of the cellular and molecular events in hormonal carcinogenesis. It has become increasingly clear that the risk of naturally occurring sex hormones in carcinogenic processes, both in human and in animal models, requires only minute quantities of hormones, at both the serum and tissue levels. Moreover, hormone target tissues for neoplastic transformation, perhaps with the exception of the liver, generally have relatively modest ability to metabolize sex hormones, such as the breast and prostate. Table 1 summarizes the serum, and in most cases, the tissue levels of sex hormones, both endogenously and exogenously ingested, which are associated with increased risk for endocrine-associated cancers such as breast, endometrium, and prostate, as well as the hormone levels of four experimental models that have been shown to elicit high tumor incidences. In contrast to the human, in which the hormone levels are cyclic, however, the latter require continuous hormone exposure at these relatively low levels.

More books from Springer New York

Cover of the book Advances in Physical Geochemistry by
Cover of the book Precision Molecular Pathology of Breast Cancer by
Cover of the book Daylight Science and Daylighting Technology by
Cover of the book Pharmaceutical Stability Testing to Support Global Markets by
Cover of the book The Hatfield Lunar Atlas by
Cover of the book Ethnic Rhinoplasty by
Cover of the book Mangrove Ecosystems of Asia by
Cover of the book Residue Reviews / Rückstands-Berichte by
Cover of the book International Handbook of Metacognition and Learning Technologies by
Cover of the book Malignant Tumors of the Thyroid by
Cover of the book Human Gametes and Preimplantation Embryos by
Cover of the book Reviews in Plasmonics 2010 by
Cover of the book In Sickness and In Health by
Cover of the book Murder and Politics in Mexico by
Cover of the book The Family in Medical Practice by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy