Industrial Scale Suspension Culture of Living Cells

Nonfiction, Science & Nature, Science, Biological Sciences, Biotechnology
Cover of the book Industrial Scale Suspension Culture of Living Cells by Hans-Peter Meyer, Diego Schmidhalter, Wiley
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Author: Hans-Peter Meyer, Diego Schmidhalter ISBN: 9783527683352
Publisher: Wiley Publication: July 30, 2014
Imprint: Wiley-Blackwell Language: English
Author: Hans-Peter Meyer, Diego Schmidhalter
ISBN: 9783527683352
Publisher: Wiley
Publication: July 30, 2014
Imprint: Wiley-Blackwell
Language: English

The submersed cultivation of organisms in sterile containments or fermenters has become the standard manufacturing procedure, and will remain the gold standard for some time to come. This book thus addresses submersed cell culture and fermentation and its importance for the manufacturing industry. It goes beyond expression systems and integrally investigates all those factors relevant for manufacturing using suspension cultures. In so doing, the contributions cover all industrial cultivation methods in a comprehensive and comparative manner, with most of the authors coming from the industry itself. Depending on the maturity of the technology, the chapters address in turn the expression system, basic process design, key factors affecting process economics, plant and bioreactor design, and regulatory aspects.

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The submersed cultivation of organisms in sterile containments or fermenters has become the standard manufacturing procedure, and will remain the gold standard for some time to come. This book thus addresses submersed cell culture and fermentation and its importance for the manufacturing industry. It goes beyond expression systems and integrally investigates all those factors relevant for manufacturing using suspension cultures. In so doing, the contributions cover all industrial cultivation methods in a comprehensive and comparative manner, with most of the authors coming from the industry itself. Depending on the maturity of the technology, the chapters address in turn the expression system, basic process design, key factors affecting process economics, plant and bioreactor design, and regulatory aspects.

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