MACPF/CDC Proteins - Agents of Defence, Attack and Invasion

Nonfiction, Science & Nature, Science, Chemistry, General Chemistry, Health & Well Being, Medical
Cover of the book MACPF/CDC Proteins - Agents of Defence, Attack and Invasion by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789401788816
Publisher: Springer Netherlands Publication: May 5, 2014
Imprint: Springer Language: English
Author:
ISBN: 9789401788816
Publisher: Springer Netherlands
Publication: May 5, 2014
Imprint: Springer
Language: English

This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes.

The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes.

The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.

More books from Springer Netherlands

Cover of the book DNA Repair of Cancer Stem Cells by
Cover of the book Construction and Building Research by
Cover of the book The Problem of Embodiment by
Cover of the book Practice and Realization by
Cover of the book Management Training in High-Tech and R&D by
Cover of the book The Social Dynamics of George H. Mead by
Cover of the book God and Evil by
Cover of the book Glomerulonephritis by
Cover of the book Predation by
Cover of the book Hazardous Child Labour in Latin America by
Cover of the book Island Ecology by
Cover of the book Through the Models of Writing by
Cover of the book Practice Management Compendium by
Cover of the book Experimental and Clinical Hepatology by
Cover of the book Creep and Hygrothermal Effects in Concrete Structures by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy