Matrix Metalloproteinase Biology

Nonfiction, Science & Nature, Science, Biological Sciences
Cover of the book Matrix Metalloproteinase Biology by , Wiley
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781118772386
Publisher: Wiley Publication: May 27, 2015
Imprint: Wiley-Blackwell Language: English
Author:
ISBN: 9781118772386
Publisher: Wiley
Publication: May 27, 2015
Imprint: Wiley-Blackwell
Language: English

Discussing recent advances in the field of matrix metalloproteinase (MMP) research from a multidisciplinary perspective, Matrix Metalloproteinase Biologyis a collection of chapters written by leaders in the field of MMPs. The book focuses on the challenges of understanding the mechanisms substrate degradation by MMPs, as well as how these enzymes are able to degrade large, highly ordered substrates such as collagen. All topics addressed are considered in relation to disease progression including roles in cancer metastasis, rheumatoid arthritis and other inflammatory diseases.

The text first provides an overview of MMPs, focusing on the history, the development and failures of small molecule inhibitors in clinical trials, and work with TIMPS, the endogenous inhibitors of MMPs. These introductory chapters establish the foundation for later discussion of the recent progress on the design of different types of inhibitors, including novel antibody based therapeutics.The following section emphasizes research using novel methods to further the study of the MMPs. The third and final section focuses on in vivo research, particularly with respect to cancer models, degradation of the extracellular matrix, and MMP involvement in other disease states.

Written and edited by leaders in the field, Matrix Metalloproteinase Biology addresses the rapidly growth in MMP research, and will be an invaluable resource to advanced students and researchers studying cell and molecular biology.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Discussing recent advances in the field of matrix metalloproteinase (MMP) research from a multidisciplinary perspective, Matrix Metalloproteinase Biologyis a collection of chapters written by leaders in the field of MMPs. The book focuses on the challenges of understanding the mechanisms substrate degradation by MMPs, as well as how these enzymes are able to degrade large, highly ordered substrates such as collagen. All topics addressed are considered in relation to disease progression including roles in cancer metastasis, rheumatoid arthritis and other inflammatory diseases.

The text first provides an overview of MMPs, focusing on the history, the development and failures of small molecule inhibitors in clinical trials, and work with TIMPS, the endogenous inhibitors of MMPs. These introductory chapters establish the foundation for later discussion of the recent progress on the design of different types of inhibitors, including novel antibody based therapeutics.The following section emphasizes research using novel methods to further the study of the MMPs. The third and final section focuses on in vivo research, particularly with respect to cancer models, degradation of the extracellular matrix, and MMP involvement in other disease states.

Written and edited by leaders in the field, Matrix Metalloproteinase Biology addresses the rapidly growth in MMP research, and will be an invaluable resource to advanced students and researchers studying cell and molecular biology.

More books from Wiley

Cover of the book On Critique by
Cover of the book Become the Real Deal, Enhanced Edition by
Cover of the book Democracy and the Global Order by
Cover of the book Simulation Techniques in Financial Risk Management by
Cover of the book Mission Impact by
Cover of the book Probabilistic Physics of Failure Approach to Reliability by
Cover of the book The Business Coaching Toolkit by
Cover of the book Smart Calling by
Cover of the book Design and Analysis of Clinical Trials by
Cover of the book Medicine and Surgery of Camelids by
Cover of the book Modern Portfolio Theory by
Cover of the book Blackwell's Five-Minute Veterinary Consult Clinical Companion by
Cover of the book Teaching How to Learn in a What-to-Learn Culture by
Cover of the book Globalization and Literature by
Cover of the book Heat Transfer to Non-Newtonian Fluids by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy