Mechanisms of Atrial Arrhythmias

Insights from the Development of a Biophysically Detailed Model of the Human Atria

Nonfiction, Science & Nature, Science, Biological Sciences, Biophysics, Health & Well Being, Medical, Specialties, Internal Medicine, Cardiology
Cover of the book Mechanisms of Atrial Arrhythmias by Michael A. Colman, Springer International Publishing
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Author: Michael A. Colman ISBN: 9783319016436
Publisher: Springer International Publishing Publication: November 4, 2013
Imprint: Springer Language: English
Author: Michael A. Colman
ISBN: 9783319016436
Publisher: Springer International Publishing
Publication: November 4, 2013
Imprint: Springer
Language: English

This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation. The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation and develops novel techniques for the monitoring of atrial tachycardia.

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This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation. The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation and develops novel techniques for the monitoring of atrial tachycardia.

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