Mitochondrial Oxidative Phosphorylation

Nuclear-Encoded Genes, Enzyme Regulation, and Pathophysiology

Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Health & Well Being, Medical, Medical Science, Genetics
Cover of the book Mitochondrial Oxidative Phosphorylation by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461435730
Publisher: Springer New York Publication: June 23, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781461435730
Publisher: Springer New York
Publication: June 23, 2012
Imprint: Springer
Language: English

This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. Most of these genes occur in eukaryotic cells, but not in bacteria or archaea. The main function of mitochondria, the synthesis of ATP, is performed at subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a regulatory function. However, the specific physiological functions of the nuclear encoded subunits of complexes I, III, IV, and V are mostly unknown. New data indicates that they are essential for life of higher organisms, which is characterized by an adult life without cell division (postmeiotic stage) in most tissues, after the juvenile growth. For complex IV (cytochrome c oxidase) some of these subunits occur in tissue-specific (subunits IV, VIa, VIb, VIIa, VIII), developmental-specific (subunits IV, VIa, and VIIa) as well as species-specific isoforms. Defective genes of some subunits were shown to induce mitochondrial diseases. Mitochondrial genes and human diseases will also be covered.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. Most of these genes occur in eukaryotic cells, but not in bacteria or archaea. The main function of mitochondria, the synthesis of ATP, is performed at subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a regulatory function. However, the specific physiological functions of the nuclear encoded subunits of complexes I, III, IV, and V are mostly unknown. New data indicates that they are essential for life of higher organisms, which is characterized by an adult life without cell division (postmeiotic stage) in most tissues, after the juvenile growth. For complex IV (cytochrome c oxidase) some of these subunits occur in tissue-specific (subunits IV, VIa, VIb, VIIa, VIII), developmental-specific (subunits IV, VIa, and VIIa) as well as species-specific isoforms. Defective genes of some subunits were shown to induce mitochondrial diseases. Mitochondrial genes and human diseases will also be covered.

More books from Springer New York

Cover of the book Google It by
Cover of the book Interventional and Endovascular Therapy of the Nervous System by
Cover of the book Recent Advancements in Gene Expression and Enabling Technologies in Crop Plants by
Cover of the book Introduction to Nursing Informatics by
Cover of the book Juvenile Delinquency in Europe and Beyond by
Cover of the book Harmonic Analysis on Symmetric Spaces—Higher Rank Spaces, Positive Definite Matrix Space and Generalizations by
Cover of the book So You Want a Meade LX Telescope! by
Cover of the book The Internet of Things by
Cover of the book Tools to Aid Environmental Decision Making by
Cover of the book Handbook of Research on Educational Communications and Technology by
Cover of the book Physical Layer Approaches for Securing Wireless Communication Systems by
Cover of the book Sustainable Supply Chains by
Cover of the book Molecular Basis for Therapy of AIDS-Defining Cancers by
Cover of the book Analysis and Design of Discrete Part Production Lines by
Cover of the book Analysis of Genetic Association Studies by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy