Molecular Oncology: Underlying Mechanisms and Translational Advancements

Nonfiction, Health & Well Being, Medical, Specialties, Oncology
Cover of the book Molecular Oncology: Underlying Mechanisms and Translational Advancements by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319530826
Publisher: Springer International Publishing Publication: March 29, 2017
Imprint: Springer Language: English
Author:
ISBN: 9783319530826
Publisher: Springer International Publishing
Publication: March 29, 2017
Imprint: Springer
Language: English

Cancer is a multifaceted and genomically complex disease and data obtained through high throughput technologies has provided near complete resolution of the landscape of how genomic, genetic and epigenetic mutations in cancerous cells effectively influence homeostasis of signaling networks within these cells, between cancerous cells, tumor microenvironment and at the organ level. Increasingly sophisticated information has helped us in developing a better understanding of the underlying mechanisms of cancer, and it is now known that intra-tumor genetic heterogeneity, cellular plasticity, dysregulation of spatio-temporally controlled signaling cascades, and loss of apoptosis are contributory in cancer development, progression and the development of resistance against different therapeutics. It is becoming progressively more understandable that earlier detection of pre-existing or emerging resistance against different therapeutics may prove to be helpful in personalizing the use of targeted cancer therapy. 

Despite the fact that there is a continuously increasing list of books, being guest edited by researchers, books on the subject are often composed of invited reviews without proper sequence and continuity and designed for a particular readership. This book progressively shifts and guides the readers from basic underlying mechanisms to translational approaches to treat cancer.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Cancer is a multifaceted and genomically complex disease and data obtained through high throughput technologies has provided near complete resolution of the landscape of how genomic, genetic and epigenetic mutations in cancerous cells effectively influence homeostasis of signaling networks within these cells, between cancerous cells, tumor microenvironment and at the organ level. Increasingly sophisticated information has helped us in developing a better understanding of the underlying mechanisms of cancer, and it is now known that intra-tumor genetic heterogeneity, cellular plasticity, dysregulation of spatio-temporally controlled signaling cascades, and loss of apoptosis are contributory in cancer development, progression and the development of resistance against different therapeutics. It is becoming progressively more understandable that earlier detection of pre-existing or emerging resistance against different therapeutics may prove to be helpful in personalizing the use of targeted cancer therapy. 

Despite the fact that there is a continuously increasing list of books, being guest edited by researchers, books on the subject are often composed of invited reviews without proper sequence and continuity and designed for a particular readership. This book progressively shifts and guides the readers from basic underlying mechanisms to translational approaches to treat cancer.

More books from Springer International Publishing

Cover of the book Raising Capital or Improving Risk Management and Efficiency? by
Cover of the book Integrated Reconfigurable Manufacturing Systems and Smart Value Chain by
Cover of the book 9-12Cr Heat-Resistant Steels by
Cover of the book Economic Policies since the Global Financial Crisis by
Cover of the book The Human Factor Approach to Managerial and Organizational Efficiency and Effectiveness by
Cover of the book Partial Least Squares Path Modeling by
Cover of the book Electric Vehicle Sharing Services for Smarter Cities by
Cover of the book Electroweak Symmetry Breaking by
Cover of the book Harvesting Rainwater from Buildings by
Cover of the book Global Corruption from a Geographic Perspective by
Cover of the book Clinical Handbook of Insomnia by
Cover of the book The Ecopoetics of Entanglement in Contemporary Turkish and American Literatures by
Cover of the book Theory of Vibration by
Cover of the book Control of Nonholonomic Systems: from Sub-Riemannian Geometry to Motion Planning by
Cover of the book Game Theory for Networks by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy