Nanoparticulate Drug Delivery

Perspectives on the Transition from Laboratory to Market

Nonfiction, Science & Nature, Technology, Engineering, Chemical & Biochemical
Cover of the book Nanoparticulate Drug Delivery by Vandana Patravale, Prajakta Dandekar, Ratnesh Jain, Elsevier Science
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Author: Vandana Patravale, Prajakta Dandekar, Ratnesh Jain ISBN: 9781908818195
Publisher: Elsevier Science Publication: October 31, 2012
Imprint: Woodhead Publishing Language: English
Author: Vandana Patravale, Prajakta Dandekar, Ratnesh Jain
ISBN: 9781908818195
Publisher: Elsevier Science
Publication: October 31, 2012
Imprint: Woodhead Publishing
Language: English

Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector. The first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers, including the assessment of their morphology, sterility and potential toxicity. In the latter part of the book, chapters cover nanotoxicology, regulatory aspect and clinical trials, ending with an overview of several case studies and a look towards future developments.

  • Discusses the issues surrounding nanoparticulate products, based on personal experience of their formulation
  • Provides an overview of new application areas, including RNA interference
  • Outlines the pros and cons of nanoparticulate products, and discusses how these may influence their route into the commercial sector
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Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector. The first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers, including the assessment of their morphology, sterility and potential toxicity. In the latter part of the book, chapters cover nanotoxicology, regulatory aspect and clinical trials, ending with an overview of several case studies and a look towards future developments.

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