Negative Co-Receptors and Ligands

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology
Cover of the book Negative Co-Receptors and Ligands by , Springer Berlin Heidelberg
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Author: ISBN: 9783642195457
Publisher: Springer Berlin Heidelberg Publication: April 11, 2011
Imprint: Springer Language: English
Author:
ISBN: 9783642195457
Publisher: Springer Berlin Heidelberg
Publication: April 11, 2011
Imprint: Springer
Language: English

Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules.

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Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules.

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