Neural Transplantation in Cerebellar Ataxia

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Neuroscience, Science & Nature, Science, Biological Sciences
Cover of the book Neural Transplantation in Cerebellar Ataxia by Lazaros Triarhou, Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Lazaros Triarhou ISBN: 9783662222133
Publisher: Springer Berlin Heidelberg Publication: November 11, 2013
Imprint: Springer Language: English
Author: Lazaros Triarhou
ISBN: 9783662222133
Publisher: Springer Berlin Heidelberg
Publication: November 11, 2013
Imprint: Springer
Language: English

erebellar ataxia is a failure in muscular coordination that re­ C sults from a slow, progressive deterioration of neurons in the cerebellum. An estimated 150,000 people are affected by the he­ reditary ataxias and related disorders in the United States. At present, there is no known cure. In an experimental treatment aimed at reconstructing the damaged pathway through exog­ enous neuronal supplementation, genetically ataxic mice have been used for intracerebral grafting of genetically healthy cerebellar neuroblasts, and evidence has been obtained for graft-induced en­ hancement of behavioral responses after bilateral cerebellar grafts. Such results are encouraging and underscore the potential of the neural grafting technique in restoring cerebellar function. How­ ever, many of the pathological and biochemical mechanisms in the interaction between grafted tissue and the host brain need to be further elucidated in extensive experimental studies, and great cau­ tion must be used in contemplating the theoretical feasibility of a possible application in humans.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

erebellar ataxia is a failure in muscular coordination that re­ C sults from a slow, progressive deterioration of neurons in the cerebellum. An estimated 150,000 people are affected by the he­ reditary ataxias and related disorders in the United States. At present, there is no known cure. In an experimental treatment aimed at reconstructing the damaged pathway through exog­ enous neuronal supplementation, genetically ataxic mice have been used for intracerebral grafting of genetically healthy cerebellar neuroblasts, and evidence has been obtained for graft-induced en­ hancement of behavioral responses after bilateral cerebellar grafts. Such results are encouraging and underscore the potential of the neural grafting technique in restoring cerebellar function. How­ ever, many of the pathological and biochemical mechanisms in the interaction between grafted tissue and the host brain need to be further elucidated in extensive experimental studies, and great cau­ tion must be used in contemplating the theoretical feasibility of a possible application in humans.

More books from Springer Berlin Heidelberg

Cover of the book Low Dimensional Semiconductor Structures by Lazaros Triarhou
Cover of the book Construction and Reactivity of Pt-Based Bi-component Catalytic Systems by Lazaros Triarhou
Cover of the book eHealth: Legal, Ethical and Governance Challenges by Lazaros Triarhou
Cover of the book Tissue Engineering by Lazaros Triarhou
Cover of the book Optimization of Solid Waste Conversion Process and Risk Control of Groundwater Pollution by Lazaros Triarhou
Cover of the book Ecological Perception Research, Visual Communication, and Aesthetics by Lazaros Triarhou
Cover of the book Transkulturelle Medizin by Lazaros Triarhou
Cover of the book MWW-Type Titanosilicate by Lazaros Triarhou
Cover of the book Schulterdystokie und Plexusparese by Lazaros Triarhou
Cover of the book The Source/Drain Engineering of Nanoscale Germanium-based MOS Devices by Lazaros Triarhou
Cover of the book Global Change by Lazaros Triarhou
Cover of the book Histological Typing of Lung and Pleural Tumours by Lazaros Triarhou
Cover of the book eHealth in Deutschland by Lazaros Triarhou
Cover of the book Breast Cancer by Lazaros Triarhou
Cover of the book Zukunftsfragen des deutschen Steuerrechts II by Lazaros Triarhou
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy