Neuroanatomy and Pathology of Sporadic Alzheimer's Disease

Nonfiction, Health & Well Being, Medical, Specialties, Pathology, Internal Medicine, Neuroscience, Science & Nature, Science
Cover of the book Neuroanatomy and Pathology of Sporadic Alzheimer's Disease by Heiko Braak, Kelly Del Tredici, Springer International Publishing
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Author: Heiko Braak, Kelly Del Tredici ISBN: 9783319126791
Publisher: Springer International Publishing Publication: December 11, 2014
Imprint: Springer Language: English
Author: Heiko Braak, Kelly Del Tredici
ISBN: 9783319126791
Publisher: Springer International Publishing
Publication: December 11, 2014
Imprint: Springer
Language: English

As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail

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As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail

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