NMR in Glycoscience and Glycotechnology

Nonfiction, Science & Nature, Science, Chemistry, Analytic, Biological Sciences, Biochemistry
Cover of the book NMR in Glycoscience and Glycotechnology by Daron I Freedberg, Anthony S Serianni, Mario Schubert, James Prestegard, J Jimenez-Barbero, Koichi Kato, Thomas Peters, Yoshiki Yamaguchi, Adam Barb, Vitor H Pomin, Xu Wang, Yu Nakagawa, Mei Hong, Marco Guerrini, Goran Widmalm, William York, Jun Kikuchi, William Price, Masatsune Kainosho, Royal Society of Chemistry
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Author: Daron I Freedberg, Anthony S Serianni, Mario Schubert, James Prestegard, J Jimenez-Barbero, Koichi Kato, Thomas Peters, Yoshiki Yamaguchi, Adam Barb, Vitor H Pomin, Xu Wang, Yu Nakagawa, Mei Hong, Marco Guerrini, Goran Widmalm, William York, Jun Kikuchi, William Price, Masatsune Kainosho ISBN: 9781788011280
Publisher: Royal Society of Chemistry Publication: May 15, 2017
Imprint: Royal Society of Chemistry Language: English
Author: Daron I Freedberg, Anthony S Serianni, Mario Schubert, James Prestegard, J Jimenez-Barbero, Koichi Kato, Thomas Peters, Yoshiki Yamaguchi, Adam Barb, Vitor H Pomin, Xu Wang, Yu Nakagawa, Mei Hong, Marco Guerrini, Goran Widmalm, William York, Jun Kikuchi, William Price, Masatsune Kainosho
ISBN: 9781788011280
Publisher: Royal Society of Chemistry
Publication: May 15, 2017
Imprint: Royal Society of Chemistry
Language: English

This volume focuses on solution and solid-state NMR of carbohydrates, glycoproteins, glyco-technologies, biomass and related topics. It is estimated that at least 80% of all proteins are glycoproteins. Because of the complexity, heterogeneity and flexibility of the sugar chains, the structural biology approaches for glycoconjugates have been generally avoided. NMR techniques although well established for structural analyses of proteins and nucleic acids, cannot be simply applied to this complex class of biomolecules. Nonetheless, recently developed NMR techniques for carbohydrates open the door to conformational studies of a variety of sugar chains of biological interest. NMR studies on glycans will have significant impact on the development of vaccines, adjuvants, therapeutics, biomarkers and on biomass regeneration.

In this volume, the Editors have collected the most up-to-date NMR applications from experts in the field of carbohydrate NMR spectroscopy. Timely and useful, not only for NMR specialists, it will appeal to researchers in the general field of structural biology, biochemistry and biophysics, molecular and cellular biology and material science.

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This volume focuses on solution and solid-state NMR of carbohydrates, glycoproteins, glyco-technologies, biomass and related topics. It is estimated that at least 80% of all proteins are glycoproteins. Because of the complexity, heterogeneity and flexibility of the sugar chains, the structural biology approaches for glycoconjugates have been generally avoided. NMR techniques although well established for structural analyses of proteins and nucleic acids, cannot be simply applied to this complex class of biomolecules. Nonetheless, recently developed NMR techniques for carbohydrates open the door to conformational studies of a variety of sugar chains of biological interest. NMR studies on glycans will have significant impact on the development of vaccines, adjuvants, therapeutics, biomarkers and on biomass regeneration.

In this volume, the Editors have collected the most up-to-date NMR applications from experts in the field of carbohydrate NMR spectroscopy. Timely and useful, not only for NMR specialists, it will appeal to researchers in the general field of structural biology, biochemistry and biophysics, molecular and cellular biology and material science.

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