Pan-cancer Integrative Molecular Portrait Towards a New Paradigm in Precision Medicine

Nonfiction, Health & Well Being, Medical, Specialties, Pathology, Oncology
Cover of the book Pan-cancer Integrative Molecular Portrait Towards a New Paradigm in Precision Medicine by , Springer International Publishing
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Author: ISBN: 9783319221892
Publisher: Springer International Publishing Publication: August 27, 2015
Imprint: Springer Language: English
Author:
ISBN: 9783319221892
Publisher: Springer International Publishing
Publication: August 27, 2015
Imprint: Springer
Language: English

This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by implementing them in daily practice. It also covers the key role of pathology in the validation of molecular results and the complex assessment of predictive biomarkers. The different topics covered are supplemented by unique concrete examples based on the SHIVA trial.

The authors are all members of the French Curie Institute, one of the world’s foremost cancer research institutions.

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This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by implementing them in daily practice. It also covers the key role of pathology in the validation of molecular results and the complex assessment of predictive biomarkers. The different topics covered are supplemented by unique concrete examples based on the SHIVA trial.

The authors are all members of the French Curie Institute, one of the world’s foremost cancer research institutions.

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