Pharmacology in Drug Discovery

Understanding Drug Response

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology, Science & Nature, Technology
Cover of the book Pharmacology in Drug Discovery by Terry Kenakin, Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Terry Kenakin ISBN: 9780123848574
Publisher: Elsevier Science Publication: September 1, 2011
Imprint: Academic Press Language: English
Author: Terry Kenakin
ISBN: 9780123848574
Publisher: Elsevier Science
Publication: September 1, 2011
Imprint: Academic Press
Language: English

Pharmacology in Drug Discovery: Understanding Drug Response is designed for all students, recent graduates, and new researchers in the pharmaceutical and biotechnology industries who need to interpret change in physiology induced by a chemical substance. Physiological systems customize chemical signal input to their own needs; therefore the same drug can have different effects in different physiological systems. The field of pharmacology is unique in that it furnishes the tools to analyze these different behaviors and traces them to their root cause. This enables predictions of drug behavior to be made in all systems, an invaluable tool for drug discovery because almost all drugs are developed in test systems far removed from the therapeutic one. 
This valuable resource provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology, allowing for more informed predictions of drug effects in all systems and forming the basis of the drug-discovery process. Chapters follow a logical progression on how to characterize the pharmacology of any given molecule, and include important terminology, chapter summaries, references, and review questions to aid the reader in understanding and retention of the material.

  • Enables the reader to interpret drug dose-response data and make mechanistic inferences at the molecular level
  • Bridges the gap between biochemistry and therapeutic medicine
  • Chapters include key topics such as drug affinity and efficacy, enzymes as drug targets, in vivo pharmacology, safety pharmacology, and more
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Pharmacology in Drug Discovery: Understanding Drug Response is designed for all students, recent graduates, and new researchers in the pharmaceutical and biotechnology industries who need to interpret change in physiology induced by a chemical substance. Physiological systems customize chemical signal input to their own needs; therefore the same drug can have different effects in different physiological systems. The field of pharmacology is unique in that it furnishes the tools to analyze these different behaviors and traces them to their root cause. This enables predictions of drug behavior to be made in all systems, an invaluable tool for drug discovery because almost all drugs are developed in test systems far removed from the therapeutic one. 
This valuable resource provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology, allowing for more informed predictions of drug effects in all systems and forming the basis of the drug-discovery process. Chapters follow a logical progression on how to characterize the pharmacology of any given molecule, and include important terminology, chapter summaries, references, and review questions to aid the reader in understanding and retention of the material.

More books from Elsevier Science

Cover of the book Handbook of Systems Biology by Terry Kenakin
Cover of the book Pharmacology of 5-HT6 receptors, Part II by Terry Kenakin
Cover of the book Thermodynamics and Statistical Mechanics by Terry Kenakin
Cover of the book Analysis, Manifolds and Physics, Part II - Revised and Enlarged Edition by Terry Kenakin
Cover of the book Desulphurization and Denitrification of Diesel Oil Using Ionic Liquids by Terry Kenakin
Cover of the book Studies in Natural Products Chemistry by Terry Kenakin
Cover of the book Morality in Context by Terry Kenakin
Cover of the book Philosophy of Technology and Engineering Sciences by Terry Kenakin
Cover of the book Parallel Computational Fluid Dynamics '99 by Terry Kenakin
Cover of the book Cardiovascular Physiology: Heart, Peripheral Circulation and Methodology by Terry Kenakin
Cover of the book Handbook of Nonwoven Filter Media by Terry Kenakin
Cover of the book The Choroid Plexus and Cerebrospinal Fluid by Terry Kenakin
Cover of the book Advances in Agronomy by Terry Kenakin
Cover of the book Some Problems of Chemical Kinetics and Reactivity by Terry Kenakin
Cover of the book Enzyme Kinetics and Mechanism, Part F: Detection and Characterization of Enzyme Reaction Intermediates by Terry Kenakin
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy