Physics at the Biomolecular Interface

Fundamentals for Molecular Targeted Therapy

Nonfiction, Science & Nature, Science, Biological Sciences, Biophysics, Chemistry, Physical & Theoretical
Cover of the book Physics at the Biomolecular Interface by Ariel Fernández, Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Ariel Fernández ISBN: 9783319308524
Publisher: Springer International Publishing Publication: May 11, 2016
Imprint: Springer Language: English
Author: Ariel Fernández
ISBN: 9783319308524
Publisher: Springer International Publishing
Publication: May 11, 2016
Imprint: Springer
Language: English

This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the book becomes uniquely positioned to address core problems in molecular biophysics. It highlights the importance of interfacial tension in delineating a solution to the protein folding problem, in unravelling the physico-chemical basis of enzyme catalysis and protein associations, and in rationally designing molecular targeted therapies. Thus grounded in fundamental science, the book develops a powerful technological platform for drug discovery, while it is set to inspire scientists at any level in their careers determined to address the major challenges in molecular biophysics.

The acknowledgment of how exquisitely the structure and dynamics of proteins and their aqueous environment are related attests to the overdue recognition that biomolecular phenomena cannot be effectively understood without dealing with interfacial behaviour. There is an urge to grasp how biologically relevant behaviour is shaped by the structuring of biomolecular interfaces and how interfacial tension affects the molecular events that take place in the cell. This book squarely addresses these needs from a physicist perspective.

The book may serve as a monograph for practitioners and, alternatively, as an advanced textbook. Fruitful reading requires a background in physical chemistry and some basics in biophysics. The selected problems at the end of the chapters and the progression in conceptual difficulty make it a suitable textbook for a graduate level course or an elective course for seniors majoring in chemistry, physics, biomedical engineering or related disciplines.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the book becomes uniquely positioned to address core problems in molecular biophysics. It highlights the importance of interfacial tension in delineating a solution to the protein folding problem, in unravelling the physico-chemical basis of enzyme catalysis and protein associations, and in rationally designing molecular targeted therapies. Thus grounded in fundamental science, the book develops a powerful technological platform for drug discovery, while it is set to inspire scientists at any level in their careers determined to address the major challenges in molecular biophysics.

The acknowledgment of how exquisitely the structure and dynamics of proteins and their aqueous environment are related attests to the overdue recognition that biomolecular phenomena cannot be effectively understood without dealing with interfacial behaviour. There is an urge to grasp how biologically relevant behaviour is shaped by the structuring of biomolecular interfaces and how interfacial tension affects the molecular events that take place in the cell. This book squarely addresses these needs from a physicist perspective.

The book may serve as a monograph for practitioners and, alternatively, as an advanced textbook. Fruitful reading requires a background in physical chemistry and some basics in biophysics. The selected problems at the end of the chapters and the progression in conceptual difficulty make it a suitable textbook for a graduate level course or an elective course for seniors majoring in chemistry, physics, biomedical engineering or related disciplines.

More books from Springer International Publishing

Cover of the book Optimal Search for Moving Targets by Ariel Fernández
Cover of the book Formal Approach to the Metaphysics of Perspectives by Ariel Fernández
Cover of the book Reframing the Transitional Justice Paradigm by Ariel Fernández
Cover of the book Doing Ethnography in Criminology by Ariel Fernández
Cover of the book Husserlian Phenomenology by Ariel Fernández
Cover of the book Database and Expert Systems Applications by Ariel Fernández
Cover of the book Solar Energy for Fuels by Ariel Fernández
Cover of the book Ego-histories of France and the Second World War by Ariel Fernández
Cover of the book Husserl und die klassische deutsche Philosophie by Ariel Fernández
Cover of the book Jane Addams: Progressive Pioneer of Peace, Philosophy, Sociology, Social Work and Public Administration by Ariel Fernández
Cover of the book Global Mental Health by Ariel Fernández
Cover of the book Advances in Hybridization of Intelligent Methods by Ariel Fernández
Cover of the book Pragmatics and Law by Ariel Fernández
Cover of the book Marine Isotope Stage 3 in Southern South America, 60 KA B.P.-30 KA B.P. by Ariel Fernández
Cover of the book Optimization in Electrical Engineering by Ariel Fernández
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy