Privileged Structures in Drug Discovery

Medicinal Chemistry and Synthesis

Nonfiction, Science & Nature, Science, Chemistry, Organic, Technical & Industrial, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Privileged Structures in Drug Discovery by Larry Yet, Wiley
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Larry Yet ISBN: 9781118686331
Publisher: Wiley Publication: March 7, 2018
Imprint: Wiley Language: English
Author: Larry Yet
ISBN: 9781118686331
Publisher: Wiley
Publication: March 7, 2018
Imprint: Wiley
Language: English

A comprehensive guide to privileged structures and their application in the discovery of new drugs

The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field.

The book describes the up-to-date and state-of-the-art methods of organic synthesis that describe the use of privileged structures that are of most interest. Chapters included information on benzodiazepines, 1,4-dihydropyridines, biaryls, 4-(hetero)arylpiperidines, spiropiperidines, 2-aminopyrimidines, 2-aminothiazoles, 2-(hetero)arylindoles, tetrahydroisoquinolines, 2,2-dimethylbenzopyrans, hydroxamates, and bicyclic pyridines containing ring-junction nitrogen as privileged scaffolds in medicinal chemistry. Numerous, illustrative case studies document the current use of the privileged structures in the discovery of drugs. This important volume:

  • Describes the drug compounds that have successfully made it to the marketplace and the chemistry associated with them
  • Offers the experience from an author who has worked in many therapeutic areas of medicinal chemistry
  • Details many of the recent developments in organic chemistry that prepare target molecules
  • Includes a wealth of medicinal chemistry case studies that clearly illustrate the use of privileged structures

Designed for use by industrial medicinal chemists and process chemists, academic organic and medicinal chemists, as well as chemistry students and faculty, Privileged Structures in Drug Discovery offers a current guide to organic synthesis methods to access the privileged structures of interest, and contains medicinal chemistry case studies that document their application.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

A comprehensive guide to privileged structures and their application in the discovery of new drugs

The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field.

The book describes the up-to-date and state-of-the-art methods of organic synthesis that describe the use of privileged structures that are of most interest. Chapters included information on benzodiazepines, 1,4-dihydropyridines, biaryls, 4-(hetero)arylpiperidines, spiropiperidines, 2-aminopyrimidines, 2-aminothiazoles, 2-(hetero)arylindoles, tetrahydroisoquinolines, 2,2-dimethylbenzopyrans, hydroxamates, and bicyclic pyridines containing ring-junction nitrogen as privileged scaffolds in medicinal chemistry. Numerous, illustrative case studies document the current use of the privileged structures in the discovery of drugs. This important volume:

Designed for use by industrial medicinal chemists and process chemists, academic organic and medicinal chemists, as well as chemistry students and faculty, Privileged Structures in Drug Discovery offers a current guide to organic synthesis methods to access the privileged structures of interest, and contains medicinal chemistry case studies that document their application.

More books from Wiley

Cover of the book Retail Business Kit For Dummies by Larry Yet
Cover of the book Persuade by Larry Yet
Cover of the book The Science of Stem Cells by Larry Yet
Cover of the book Creative Writing Exercises For Dummies by Larry Yet
Cover of the book Simulation and Modeling of Systems of Systems by Larry Yet
Cover of the book Clinical Psychology by Larry Yet
Cover of the book Polymer Adhesion, Friction, and Lubrication by Larry Yet
Cover of the book The Profession of Modeling and Simulation by Larry Yet
Cover of the book Fundamentals of Infection Prevention and Control by Larry Yet
Cover of the book Conversations with Zygmunt Bauman by Larry Yet
Cover of the book Hacking For Dummies by Larry Yet
Cover of the book Intramolecular Charge Transfer by Larry Yet
Cover of the book Principles of Gene Manipulation and Genomics by Larry Yet
Cover of the book Rapid Clinical Pharmacology by Larry Yet
Cover of the book High Temperature Ceramic Matrix Composites 8 by Larry Yet
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy