Reviews of Physiology, Biochemistry and Pharmacology 156

Nonfiction, Health & Well Being, Medical, Medical Science, Physiology
Cover of the book Reviews of Physiology, Biochemistry and Pharmacology 156 by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783540331469
Publisher: Springer Berlin Heidelberg Publication: May 23, 2007
Imprint: Springer Language: English
Author:
ISBN: 9783540331469
Publisher: Springer Berlin Heidelberg
Publication: May 23, 2007
Imprint: Springer
Language: English

Gastric acid plays a primary role in digestion as well as in the sterilization of food and water. Gastric juice contains the most concentrated physiological acid solution (pH~1) as a result + – of H and Cl ion secretion [hydrochloric acid (HCl) production] by parietal cells in the oxyntic mucosa of the stomach. The combined output of the parietal cells leads to the sec- tion of 1–2 l of HCl at a concentration of 150–160 mmol/l into the interior of the stomach. In order to facilitate the production of acid, the parietal cell relies on the generation of a high + concentration of H ions that are transported into the lumen of the gland. This process is fa- + + cilitated by activation of the gastric H ,K -ATPase, which translocates to the apical pole of + – the parietal cell. K as well as ATP hydrolysis and Cl all play critical roles in the activation + + of gastric H ,K -ATPase and are essential for the functioning of the enzyme (Reenstra and Forte 1990). This review will examine the classical proteins that have been linked to acid secretion as well as some recently identi?ed proteins that may modulate gastric acid secretion, in - dition we discuss the known secretagogues, and their receptors including a new receptor, which upon stimulation can lead to acid secretion.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Gastric acid plays a primary role in digestion as well as in the sterilization of food and water. Gastric juice contains the most concentrated physiological acid solution (pH~1) as a result + – of H and Cl ion secretion [hydrochloric acid (HCl) production] by parietal cells in the oxyntic mucosa of the stomach. The combined output of the parietal cells leads to the sec- tion of 1–2 l of HCl at a concentration of 150–160 mmol/l into the interior of the stomach. In order to facilitate the production of acid, the parietal cell relies on the generation of a high + concentration of H ions that are transported into the lumen of the gland. This process is fa- + + cilitated by activation of the gastric H ,K -ATPase, which translocates to the apical pole of + – the parietal cell. K as well as ATP hydrolysis and Cl all play critical roles in the activation + + of gastric H ,K -ATPase and are essential for the functioning of the enzyme (Reenstra and Forte 1990). This review will examine the classical proteins that have been linked to acid secretion as well as some recently identi?ed proteins that may modulate gastric acid secretion, in - dition we discuss the known secretagogues, and their receptors including a new receptor, which upon stimulation can lead to acid secretion.

More books from Springer Berlin Heidelberg

Cover of the book Automotive Development Processes by
Cover of the book Surface Patterning with Colloidal Monolayers by
Cover of the book Olivocerebellar Projection by
Cover of the book Theory of Phase Transitions in Polypeptides and Proteins by
Cover of the book Natural Disasters in China by
Cover of the book Quantum Theory and Reality by
Cover of the book Materials for High Temperature Engineering Applications by
Cover of the book Wild Crop Relatives: Genomic and Breeding Resources by
Cover of the book Der verborgene Hunger by
Cover of the book Methoden für die klinische Forschung und diagnostische Praxis by
Cover of the book Mechanical Forces: Their Effects on Cells and Tissues by
Cover of the book Service-Oriented Computing – ICSOC 2015 Workshops by
Cover of the book Neurophysiologische Behandlung bei Erwachsenen by
Cover of the book Der angstfreie Operationssaal by
Cover of the book Arbeitsbuch Höhere Mathematik in Rezepten by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy