Reviews of Physiology, Biochemistry and Pharmacology 156

Nonfiction, Health & Well Being, Medical, Medical Science, Physiology
Cover of the book Reviews of Physiology, Biochemistry and Pharmacology 156 by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783540331469
Publisher: Springer Berlin Heidelberg Publication: May 23, 2007
Imprint: Springer Language: English
Author:
ISBN: 9783540331469
Publisher: Springer Berlin Heidelberg
Publication: May 23, 2007
Imprint: Springer
Language: English

Gastric acid plays a primary role in digestion as well as in the sterilization of food and water. Gastric juice contains the most concentrated physiological acid solution (pH~1) as a result + – of H and Cl ion secretion [hydrochloric acid (HCl) production] by parietal cells in the oxyntic mucosa of the stomach. The combined output of the parietal cells leads to the sec- tion of 1–2 l of HCl at a concentration of 150–160 mmol/l into the interior of the stomach. In order to facilitate the production of acid, the parietal cell relies on the generation of a high + concentration of H ions that are transported into the lumen of the gland. This process is fa- + + cilitated by activation of the gastric H ,K -ATPase, which translocates to the apical pole of + – the parietal cell. K as well as ATP hydrolysis and Cl all play critical roles in the activation + + of gastric H ,K -ATPase and are essential for the functioning of the enzyme (Reenstra and Forte 1990). This review will examine the classical proteins that have been linked to acid secretion as well as some recently identi?ed proteins that may modulate gastric acid secretion, in - dition we discuss the known secretagogues, and their receptors including a new receptor, which upon stimulation can lead to acid secretion.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Gastric acid plays a primary role in digestion as well as in the sterilization of food and water. Gastric juice contains the most concentrated physiological acid solution (pH~1) as a result + – of H and Cl ion secretion [hydrochloric acid (HCl) production] by parietal cells in the oxyntic mucosa of the stomach. The combined output of the parietal cells leads to the sec- tion of 1–2 l of HCl at a concentration of 150–160 mmol/l into the interior of the stomach. In order to facilitate the production of acid, the parietal cell relies on the generation of a high + concentration of H ions that are transported into the lumen of the gland. This process is fa- + + cilitated by activation of the gastric H ,K -ATPase, which translocates to the apical pole of + – the parietal cell. K as well as ATP hydrolysis and Cl all play critical roles in the activation + + of gastric H ,K -ATPase and are essential for the functioning of the enzyme (Reenstra and Forte 1990). This review will examine the classical proteins that have been linked to acid secretion as well as some recently identi?ed proteins that may modulate gastric acid secretion, in - dition we discuss the known secretagogues, and their receptors including a new receptor, which upon stimulation can lead to acid secretion.

More books from Springer Berlin Heidelberg

Cover of the book Therapeutic Strategies in Primary and Metastatic Liver Cancer by
Cover of the book Innovation Management in Knowledge Intensive Business Services in China by
Cover of the book Ultrasound Diagnosis in Obstetrics and Gynecology by
Cover of the book Spinal Angiomas by
Cover of the book Photophysics of Organometallics by
Cover of the book Cell Proliferation and Cytogenesis in the Mouse Hippocampus by
Cover of the book Photophysics of Ionic Biochromophores by
Cover of the book Social Security and Economic Globalization by
Cover of the book Terminal Ballistics by
Cover of the book Management moralischer Risiken in Unternehmen by
Cover of the book Business Continuity by
Cover of the book EcoProduction and Logistics by
Cover of the book Medical and Surgical Management of Tachyarrhythmias by
Cover of the book Unsaponifiable Matter in Plant Seed Oils by
Cover of the book Bioökonomie für Einsteiger by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy