Role of Nutritional Supplements in promoting Muscle Hypertrophy

Nonfiction, Science & Nature, Science, Biological Sciences, Cytology
Cover of the book Role of Nutritional Supplements in promoting Muscle Hypertrophy by Tushar Chatterji, GRIN Verlag
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Tushar Chatterji ISBN: 9783656149811
Publisher: GRIN Verlag Publication: March 12, 2012
Imprint: GRIN Verlag Language: English
Author: Tushar Chatterji
ISBN: 9783656149811
Publisher: GRIN Verlag
Publication: March 12, 2012
Imprint: GRIN Verlag
Language: English

Essay from the year 2011 in the subject Biology - Cytology, grade: C, University of Glasgow (Institute of Cardiovascular and Medical Sciences), course: MRes Biomedical Sciences, language: English, abstract: The skeletal muscle is an integral part of our system. It not only acts as the storage reservoir of amino acids, but also serves as the site for protein synthesis and protein breakdown [36]. The rate of protein synthesis needs to exceed protein degradation to achieve muscle hypertrophy [18, 24]. The timing of protein intake, type and quantity play a significant role in achieving optimal outcomes when applied to resistance exercise [36]. Research has been going on since the past decade demonstrating the role of nutritional supplements like whey protein, soy, branched-chain amino acids (BCAAs, especially leucine) and creatine on protein synthesis before, during and after a bout of resistance exercise through careful investigations into intracellular signalling pathways like the mammalian target of rapamycin (mTOR) and its downstream targets-ribosomal protein S6 (kinase-1) and 4E binding protein (4E-BP1) [7, 18]. Intracellular signalling, amongst other variables, involves three essential components-abundant ATP in muscle for providing energy, insulin signalling and leucine (figure 1) [36, 37]. mTOR, regarded as the 'key regulator' of translation comprises mTORC1 and mTORC2 [36]. mTORC1 plays a significant role in promoting muscular hypertrophy via phosphorylation of S6K1 and 4E-BP1 which prevent binding of the eukaryotic initiation factor (eIF) 4E to 4E-BP1 allowing a complex formation with eIF4G (eIF4E-eIF4G) thus enhancing protein synthesis [5, 34]. This report highlights how whey proteins and BCAA (leucine) affect muscle protein synthesis via intracellular signalling pathways thereby contributing significant effects on muscular hypertrophy.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Essay from the year 2011 in the subject Biology - Cytology, grade: C, University of Glasgow (Institute of Cardiovascular and Medical Sciences), course: MRes Biomedical Sciences, language: English, abstract: The skeletal muscle is an integral part of our system. It not only acts as the storage reservoir of amino acids, but also serves as the site for protein synthesis and protein breakdown [36]. The rate of protein synthesis needs to exceed protein degradation to achieve muscle hypertrophy [18, 24]. The timing of protein intake, type and quantity play a significant role in achieving optimal outcomes when applied to resistance exercise [36]. Research has been going on since the past decade demonstrating the role of nutritional supplements like whey protein, soy, branched-chain amino acids (BCAAs, especially leucine) and creatine on protein synthesis before, during and after a bout of resistance exercise through careful investigations into intracellular signalling pathways like the mammalian target of rapamycin (mTOR) and its downstream targets-ribosomal protein S6 (kinase-1) and 4E binding protein (4E-BP1) [7, 18]. Intracellular signalling, amongst other variables, involves three essential components-abundant ATP in muscle for providing energy, insulin signalling and leucine (figure 1) [36, 37]. mTOR, regarded as the 'key regulator' of translation comprises mTORC1 and mTORC2 [36]. mTORC1 plays a significant role in promoting muscular hypertrophy via phosphorylation of S6K1 and 4E-BP1 which prevent binding of the eukaryotic initiation factor (eIF) 4E to 4E-BP1 allowing a complex formation with eIF4G (eIF4E-eIF4G) thus enhancing protein synthesis [5, 34]. This report highlights how whey proteins and BCAA (leucine) affect muscle protein synthesis via intracellular signalling pathways thereby contributing significant effects on muscular hypertrophy.

More books from GRIN Verlag

Cover of the book Berichts- und Dokumentationspflichten des Wirtschaftsprüfers im Rahmen der Abschlussprüfung by Tushar Chatterji
Cover of the book Imago Turci. Das europäische Türkenbild 1453-1600 by Tushar Chatterji
Cover of the book The Sarbanes- Oxley Act - A brief introduction by Tushar Chatterji
Cover of the book Vergleich von linearer, Tagesgebrauchtwert- und RRC-Abschreibung bei konstanten und veränderlichen Preisen by Tushar Chatterji
Cover of the book Vom Partisanenverband zum Hegemon by Tushar Chatterji
Cover of the book A critical evaluation of Michael Porter's five forces framework. Case study of the Vietnamese textile industry by Tushar Chatterji
Cover of the book The Historical Development of Japanese Investment in Singapore 1979-2007 by Tushar Chatterji
Cover of the book Tanztherapie nach Trudi Schoop by Tushar Chatterji
Cover of the book Die Missionierung durch die Jesuiten in Paraguay. Ein Utopia der Renaissance? by Tushar Chatterji
Cover of the book Universalität der Menschenrechte by Tushar Chatterji
Cover of the book Basel III - Kritische Würdigung neuer Eigenkapitalvorschriften für Banken by Tushar Chatterji
Cover of the book Gesetzgebung im Föderalismus am Beispiel des BKA-Gesetzes in Deutschland by Tushar Chatterji
Cover of the book Drogen- und Beschaffungsprostitution. Handlungsmöglichkeiten der sozialen Arbeit am Beispiel Streetwork by Tushar Chatterji
Cover of the book Das Konzept der Bewährung auf dem Prüfstand by Tushar Chatterji
Cover of the book Wirtschaftsberichterstattung: Höllenfeuer & Fix und Clever by Tushar Chatterji
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy