Synthesis of new isatin derivatives for possible CNS activity

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Synthesis of new isatin derivatives for possible CNS activity by Kiran Gangarapu, GRIN Verlag
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Kiran Gangarapu ISBN: 9783656622727
Publisher: GRIN Verlag Publication: March 25, 2014
Imprint: GRIN Verlag Language: English
Author: Kiran Gangarapu
ISBN: 9783656622727
Publisher: GRIN Verlag
Publication: March 25, 2014
Imprint: GRIN Verlag
Language: English

Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, grade: 10, , course: M-Pharmacy, language: English, abstract: Isatin (1H-indole-2,3-dione) (I) was first discovered by Erdmann and Laurent in 1841, independently as a product from oxidation of indigo by nitric and chromic acids. It is a unique molecule possessing both amide and keto carbonyl groups. Apart from this, it has an active hydrogen atom attached to nitrogen (or oxygen) and an aromatic ring which was substituted at 5- and 7-positions. It exists in a tautomeric form (II) and these functional characteristics play an important role in governing the various reactions of the molecule. The C-3 carbonyl group of isatin is strongly electrophilic. As a result, isatins are readily involved in condensation and addition reactions with carbanion type nucleophiles into 3-substituted oxindoles. In general, there are three possibilities during condensation reactions. [...]

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, grade: 10, , course: M-Pharmacy, language: English, abstract: Isatin (1H-indole-2,3-dione) (I) was first discovered by Erdmann and Laurent in 1841, independently as a product from oxidation of indigo by nitric and chromic acids. It is a unique molecule possessing both amide and keto carbonyl groups. Apart from this, it has an active hydrogen atom attached to nitrogen (or oxygen) and an aromatic ring which was substituted at 5- and 7-positions. It exists in a tautomeric form (II) and these functional characteristics play an important role in governing the various reactions of the molecule. The C-3 carbonyl group of isatin is strongly electrophilic. As a result, isatins are readily involved in condensation and addition reactions with carbanion type nucleophiles into 3-substituted oxindoles. In general, there are three possibilities during condensation reactions. [...]

More books from GRIN Verlag

Cover of the book Die Rolle des Transvestiten bei Almodóvar by Kiran Gangarapu
Cover of the book Die Getriebemontage im JD-Werk Mannheim by Kiran Gangarapu
Cover of the book Organisationsdiagnostik: Mitarbeiterbefragungen und ihre Folgemaßnahmen. Jahres- und Branchenvergleich by Kiran Gangarapu
Cover of the book Heide Wunder, Er ist die Sonn', sie ist der Mond. Frauen in der Frühen Neuzeit by Kiran Gangarapu
Cover of the book Why Students are Punished in Schools: Missing Learning Link by Kiran Gangarapu
Cover of the book Buddhismus und das Bedürfnis der modernen Zeit by Kiran Gangarapu
Cover of the book Interkulturelle Kommunikation und Deutsch als Fremdsprache by Kiran Gangarapu
Cover of the book Wasserundurchlässige Schalungsanker by Kiran Gangarapu
Cover of the book Die Gemeinsame Außen- und Sicherheitspolitik (GASP) und die Europäische Sicherheits- und Verteidigungspolitik (ESVP) by Kiran Gangarapu
Cover of the book Verbesserung der Kooperation im Sportunterricht by Kiran Gangarapu
Cover of the book Mieterinsolvenz by Kiran Gangarapu
Cover of the book Offene Arbeit mit Kindern und Jugendlichen im ländlichen Raum - Ausarbeitung zum 20-wöchigen Praxissemester by Kiran Gangarapu
Cover of the book Der Begriff der Freiheit bei Thomas Hobbes by Kiran Gangarapu
Cover of the book Die Reform der Lehrerausbildung - Defizite der Lehrerausbildung in Deutschland by Kiran Gangarapu
Cover of the book Wirtschaftsprüfung - Praktikumsbericht by Kiran Gangarapu
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy