The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy

Nonfiction, Health & Well Being, Medical, Medical Science, Genetics, Specialties, Internal Medicine, Neuroscience, Science & Nature, Science
Cover of the book The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf, Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf ISBN: 9783319192857
Publisher: Springer International Publishing Publication: September 29, 2015
Imprint: Springer Language: English
Author: Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
ISBN: 9783319192857
Publisher: Springer International Publishing
Publication: September 29, 2015
Imprint: Springer
Language: English

This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.

More books from Springer International Publishing

Cover of the book Primer on Client-Side Web Security by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Nanotechnology: Principles and Practices by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Metal Scrappers and Thieves by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Media in the Middle East by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Histamine Receptors by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book PARP Inhibitors for Cancer Therapy by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Primate Hearing and Communication by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Advances in Metaheuristic Algorithms for Optimal Design of Structures by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Metric Diffusion Along Foliations by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Understanding Flood Preparedness by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Outskirts of Galaxies by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Scripting Approaches in Mathematics Education by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Healthcare Information Management Systems by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Strongly Nonlinear Oscillators by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
Cover of the book Cross-Cultural Dialogue as a Conflict Management Strategy by Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy