The Sodium Theory Revisited

Or 45 Years of a Full Time Cnrs Neurophysiologist

Biography & Memoir, Reference
Cover of the book The Sodium Theory Revisited by Yves Pichon, Xlibris UK
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Yves Pichon ISBN: 9781479793723
Publisher: Xlibris UK Publication: March 25, 2013
Imprint: Xlibris UK Language: English
Author: Yves Pichon
ISBN: 9781479793723
Publisher: Xlibris UK
Publication: March 25, 2013
Imprint: Xlibris UK
Language: English

The sodium theory revisited (45 years of a full time CNRS neurophysiologist). The sodium theory has been elegantly proposed by Hodkin, Huxley and Katz in the early fifties, after their experiments on Plymouth squids, to account for the role of sodium and potassium ions in nerve activity. Since then, the electrophysiological techniques and the data acquisition techniques have known an amazing development. In this short paper, Yves Pichon wants to give an account of what happened since then in different laboratories (mostly marine) with a variety invertebrate species and mostly insects. One of the most important technical development has been the use of single cockroach axons which have been found to behave very much like squid axons. Another, almost simultaneous development which revealed extremely useful for the understanding of the nerve function was in situ microelectrode recording which enables an indirect analysis of the extraaxonal environement. Experiments on several species indicate that the CNS is protected from the ionic environment by a blood-brain barrier. On the other hand, quite unexpectedly, little ion accumation is detected in the vicinity of the axonal membrane in physiological conditions. Another innovating technique was the 'patch-clamp' technique which enables the recording of the activity of individual ionic channels in cultured neurones. The last chapter of this report is devoted to different mechansims leading to repetitive activity through modificatrion of the sodium and potassium axonal conductances.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The sodium theory revisited (45 years of a full time CNRS neurophysiologist). The sodium theory has been elegantly proposed by Hodkin, Huxley and Katz in the early fifties, after their experiments on Plymouth squids, to account for the role of sodium and potassium ions in nerve activity. Since then, the electrophysiological techniques and the data acquisition techniques have known an amazing development. In this short paper, Yves Pichon wants to give an account of what happened since then in different laboratories (mostly marine) with a variety invertebrate species and mostly insects. One of the most important technical development has been the use of single cockroach axons which have been found to behave very much like squid axons. Another, almost simultaneous development which revealed extremely useful for the understanding of the nerve function was in situ microelectrode recording which enables an indirect analysis of the extraaxonal environement. Experiments on several species indicate that the CNS is protected from the ionic environment by a blood-brain barrier. On the other hand, quite unexpectedly, little ion accumation is detected in the vicinity of the axonal membrane in physiological conditions. Another innovating technique was the 'patch-clamp' technique which enables the recording of the activity of individual ionic channels in cultured neurones. The last chapter of this report is devoted to different mechansims leading to repetitive activity through modificatrion of the sodium and potassium axonal conductances.

More books from Xlibris UK

Cover of the book King David His Times and Our Life by Yves Pichon
Cover of the book Leadership and Social Change by Yves Pichon
Cover of the book Gonja, the Mandingoes of Ghana by Yves Pichon
Cover of the book What Do You Know About Asthma? by Yves Pichon
Cover of the book The Seven Components of the Will of God by Yves Pichon
Cover of the book Searching for Solace by Yves Pichon
Cover of the book When the Love Has Gone by Yves Pichon
Cover of the book Short Stories 2 by Yves Pichon
Cover of the book Out of the Blue by Yves Pichon
Cover of the book Bishops by Yves Pichon
Cover of the book A Rare Duo by Yves Pichon
Cover of the book Bronze by Yves Pichon
Cover of the book Caractacus by Yves Pichon
Cover of the book Icicle Child by Yves Pichon
Cover of the book Nuthouse Episode by Yves Pichon
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy