Tumor Dormancy, Quiescence, and Senescence, Vol. 3

Aging, Cancer, and Noncancer Pathologies

Nonfiction, Science & Nature, Science, Biological Sciences, Health & Well Being, Medical
Cover of the book Tumor Dormancy, Quiescence, and Senescence, Vol. 3 by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789401793254
Publisher: Springer Netherlands Publication: September 12, 2014
Imprint: Springer Language: English
Author:
ISBN: 9789401793254
Publisher: Springer Netherlands
Publication: September 12, 2014
Imprint: Springer
Language: English

This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia protein and its role in premature senescence. The final section explores the role of senescence and autophagy in age-related cardiovascular diseases and the observation that autophagy seems to retard cardiac senescence. Like the two preceding volumes in the series, Volume 3 stands out for its comprehensive approach, its roster of some 26 expert contributors representing seven different countries and its up-to-date review of leading-edge technology and methods.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia protein and its role in premature senescence. The final section explores the role of senescence and autophagy in age-related cardiovascular diseases and the observation that autophagy seems to retard cardiac senescence. Like the two preceding volumes in the series, Volume 3 stands out for its comprehensive approach, its roster of some 26 expert contributors representing seven different countries and its up-to-date review of leading-edge technology and methods.

More books from Springer Netherlands

Cover of the book Forest Hydrology and Catchment Management by
Cover of the book Proclus: Alcibiades I by
Cover of the book Issues and Challenges in Science Education Research by
Cover of the book Solutions on Embedded Systems by
Cover of the book Re-negotiating Gender by
Cover of the book Oxidative Stress and Redox Regulation by
Cover of the book Molecular Methods for Microbial Identification and Typing by
Cover of the book Critical Communities and Aesthetic Practices by
Cover of the book Knowing and the Mystique of Logic and Rules by
Cover of the book Seed Dispersal by Ants in a Deciduous Forest Ecosystem by
Cover of the book An Integrated Assessment of China’s Ecological Restoration Programs by
Cover of the book Intergovernmental Fiscal Relations by
Cover of the book Sustainable Food Security in the Era of Local and Global Environmental Change by
Cover of the book Agora, Academy, and the Conduct of Philosophy by
Cover of the book Antibiotics in Obstetrics and Gynecology by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy