Tumor Dormancy, Quiescence, and Senescence, Vol. 3

Aging, Cancer, and Noncancer Pathologies

Nonfiction, Science & Nature, Science, Biological Sciences, Health & Well Being, Medical
Cover of the book Tumor Dormancy, Quiescence, and Senescence, Vol. 3 by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789401793254
Publisher: Springer Netherlands Publication: September 12, 2014
Imprint: Springer Language: English
Author:
ISBN: 9789401793254
Publisher: Springer Netherlands
Publication: September 12, 2014
Imprint: Springer
Language: English

This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia protein and its role in premature senescence. The final section explores the role of senescence and autophagy in age-related cardiovascular diseases and the observation that autophagy seems to retard cardiac senescence. Like the two preceding volumes in the series, Volume 3 stands out for its comprehensive approach, its roster of some 26 expert contributors representing seven different countries and its up-to-date review of leading-edge technology and methods.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia protein and its role in premature senescence. The final section explores the role of senescence and autophagy in age-related cardiovascular diseases and the observation that autophagy seems to retard cardiac senescence. Like the two preceding volumes in the series, Volume 3 stands out for its comprehensive approach, its roster of some 26 expert contributors representing seven different countries and its up-to-date review of leading-edge technology and methods.

More books from Springer Netherlands

Cover of the book Methodological Aspects of the Development of Low Temperature Physics 1881–1956 by
Cover of the book Urinary Tract Infections by
Cover of the book Terahertz and Mid Infrared Radiation: Detection of Explosives and CBRN (Using Terahertz) by
Cover of the book The Minimal Cell by
Cover of the book Global Change and the Function and Distribution of Wetlands by
Cover of the book Vascular Tumors and Malformations of the Ocular Fundus by
Cover of the book Britain and the Netherlands by
Cover of the book Peirce and Biosemiotics by
Cover of the book Conjunctions of Mind, Soul and Body from Plato to the Enlightenment by
Cover of the book The River Basin in History and Law by
Cover of the book Stephan Körner — Philosophical Analysis and Reconstruction by
Cover of the book The Realism-Antirealism Debate in the Age of Alternative Logics by
Cover of the book The Categories and the Principle of Coherence by
Cover of the book The Ecology of Urban Habitats by
Cover of the book Drug Use Trajectories Among Minority Youth by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy