Vitamin D and Cancer

Nonfiction, Science & Nature, Science, Biological Sciences, Biochemistry, Health & Well Being, Medical, Specialties, Oncology
Cover of the book Vitamin D and Cancer by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781441971883
Publisher: Springer New York Publication: December 9, 2010
Imprint: Springer Language: English
Author:
ISBN: 9781441971883
Publisher: Springer New York
Publication: December 9, 2010
Imprint: Springer
Language: English

Substantial data indicate the broad importance of vitamin D-based signaling in normal human physiology and the broad effects of vitamin D deficiency. Vitamin D may play a role not only in the control of bone and mineral metabolism, but also appears to be involved in immune function, cardiovascular health, thrombosis and vasculogenesis and neuromuscular function. Considerable epidemiologic data demonstrate that low vitamin D serum levels occur very commonly in normal adult populations and that vitamin D deficiency is associated with an enhanced risk of cancer death from lung, prostate, head & neck, colorectal and other gastrointestinal cancers. In addition, preclinical data provide evidence that calcitriol and other active analogues of calcitriol have anti-proliferative, pro-differentiative, pro-apoptotic and anti-angiogenic activity in numerous in-vitro and in-vivo models. It is quite clear that, while it requires high exposure to calcitriol to induce these effects, such exposure can be readily achieved when high dose intermittent therapy is given.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Substantial data indicate the broad importance of vitamin D-based signaling in normal human physiology and the broad effects of vitamin D deficiency. Vitamin D may play a role not only in the control of bone and mineral metabolism, but also appears to be involved in immune function, cardiovascular health, thrombosis and vasculogenesis and neuromuscular function. Considerable epidemiologic data demonstrate that low vitamin D serum levels occur very commonly in normal adult populations and that vitamin D deficiency is associated with an enhanced risk of cancer death from lung, prostate, head & neck, colorectal and other gastrointestinal cancers. In addition, preclinical data provide evidence that calcitriol and other active analogues of calcitriol have anti-proliferative, pro-differentiative, pro-apoptotic and anti-angiogenic activity in numerous in-vitro and in-vivo models. It is quite clear that, while it requires high exposure to calcitriol to induce these effects, such exposure can be readily achieved when high dose intermittent therapy is given.

More books from Springer New York

Cover of the book Working Knowledge by
Cover of the book Information Retrieval: A Health and Biomedical Perspective by
Cover of the book Societal Dynamics by
Cover of the book Alcoholism by
Cover of the book Cognitive and Psychometric Analysis of Analogical Problem Solving by
Cover of the book Hot Stove Economics by
Cover of the book Reviews of Environmental Contamination and Toxicology by
Cover of the book Evidence-Based School Mental Health Services by
Cover of the book Computational Intelligence in Biomedical Imaging by
Cover of the book Robotic Surgery of the Bladder by
Cover of the book Non-Invasive Sperm Selection for In Vitro Fertilization by
Cover of the book Management of Bladder Cancer by
Cover of the book Stearoyl-CoA Desaturase Genes in Lipid Metabolism by
Cover of the book Taurine 8 by
Cover of the book Spatio-Temporal Data Streams by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy